DRSC/TRiP Functional Genomics Resources

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Protein Alignment MARK3 and KP78b

DIOPT Version :10

Sequence 1:NP_001122390.2 Gene:MARK3 / 4140 HGNCID:6897 Length:753 Species:Homo sapiens
Sequence 2:NP_650065.1 Gene:KP78b / 41361 FlyBaseID:FBgn0026063 Length:604 Species:Drosophila melanogaster


Alignment Length:95 Identity:22/95 - (23%)
Similarity:32/95 - (33%) Gaps:30/95 - (31%)


- Green bases have known domain annotations that are detailed below.


Human    32 KLFGKVPLRETAQKDSKKTQKEYEDKAGRPSRPP-------SPKQ----------NVRKNLDFEP 79
            ||.|...:..||:..|.:::..:|.........|       ||:.          |...:|.:.|
  Fly   151 KLTGDYGVHSTARCYSPESRTSHEMLVSYSQSAPHSNANSSSPQMNGSMQRVKAYNYPDSLLYSP 215

Human    80 LSTTALILE-------------DRPANLPA 96
            ..||:.|.|             |.|.|.||
  Fly   216 AGTTSSIAETNSSGNGATRAQCDSPNNAPA 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MARK3NP_001122390.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..36 2/3 (67%)
STKc_MARK 55..307 CDD:270974 16/72 (22%)
UBA_MARK3_4 325..367 CDD:270590
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 370..600
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 632..655
MARK1-3_C 654..751 CDD:213381
KP78bNP_650065.1 Protein Kinases, catalytic domain 63..314 CDD:473864 22/95 (23%)
UBA_MARK_Par1 335..373 CDD:270522
Blue background indicates that the domain is not in the aligned region.

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