Protein Alignment MARK3 and CG9222

DIOPT Version :10

• Sequence 1: NP_001122390.2
• Gene: MARK3 / 4140
• HGNCID: 6897
• Length: 753
• Species: Homo sapiens
• Sequence 2: NP_608999.2
• Gene: CG9222 / 33867
• FlyBaseID: FBgn0031784
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 102/258 - (39%)
• Similarity: 157/258 - (60%)
• Gaps: 16/258 - (6%)

Human    60 KTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPNIVKLFEVIE 123
            |.||.||:||||:......|:.||:|||.|.:......|| |.||:..:|.|:|.|::..::.||
  Fly    80 KVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIE 144

Human   124 TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
            |...:||||:.|..|.:.||:.....:.|.::|:.|:|:||||:|.|.|.:||||:|.||||||.
  Fly   145 TSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDE 209

Human   189 DMNIKIADFGFSNEFT-------VGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL 246
            :.|:|:.||||:.:.|       :..|  |||||..||:||:.:|..||....|:|:.||:.|.:
  Fly   210 NWNLKLIDFGFARKDTRTSDNQVILSK--TFCGSYAYASPEILKGVAYDPFMSDIWACGVVCYAM 272

Human   247 VSGSLPFDGQNLKELRERVLRGKY--RIPFYMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRW 306
            |.|.||:||.|:..|.:|:.:...  :.| ..|::|::::..  :|.|:| |..:.|:.:|.|
  Fly   273 VFGRLPYDGSNVHILLKRINQSLVFPKSP-SASSECKHMIMH--ILAPVKIRYNIPQVKEDPW 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MARK3	NP_001122390.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		STKc_MARK	55..307	CDD:270974	102/258 (40%)
		UBA_MARK3_4	325..367	CDD:270590
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..600
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	632..655
		MARK1-3_C	654..751	CDD:213381
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	102/258 (40%)