Protein Alignment Elp1 and elp1

DIOPT Version :10

• Sequence 1: NP_001262478.1
• Gene: Elp1 / 41399
• FlyBaseID: FBgn0037926
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_012812382.1
• Gene: elp1 / 100170442
• XenbaseID: XB-GENE-5813351
• Length: 1326
• Species: Xenopus tropicalis
• Alignment Length: 1352
• Identity: 424/1352 - (31%)
• Similarity: 678/1352 - (50%)
• Gaps: 207/1352 - (15%)

  Fly     1 MRNLKLRYCKELN---AVAHPQHLLLQPE-----LNGGASDIYF------VVADNKIYA---VQE 48
            ||||||:.|...|   ::..||...::.|     :..|...:.|      ::.|..:.|   :.|
 Frog     1 MRNLKLKRCLRFNTSGSLGSPQCSAIRSETGTVLIGSGYGFVEFDPNSQEIIKDISLTAANFLPE 65

  Fly    49 SGDVRLKVIADLPDIVGVEFLQLDNAICVASGAGEVILVDPQTGATSEGTFCDVGIESMAWSPNQ 113
            .|:..|..|.|:||         ..::|||:..|:|:|.:..||........|.||.:|:|||:|
 Frog    66 DGNGHLVGIQDVPD---------QESVCVATSTGDVLLSNINTGQLECVGSVDSGILAMSWSPDQ 121

  Fly   114 EVVAFVTRTHNVVLMTSTFDVIAEQPLDAELDPDQQFVNVGWGKKETQFHGSEGKQAAKQKESDS 178
            |:|..||....::|||..|:.|||:.:..:...:::|:.:|||||||||||||||:||:||
 Frog   122 ELVLLVTGQQTLILMTKDFEPIAEKSIYQDDFGEEKFITLGWGKKETQFHGSEGKKAAQQK---- 182

  Fly   179 TFIRDEQELNQFTPQDVSISWRGDGEFFVVSYVAAQLG-RTFKVYDSEGKLNHTAEKSANLKDSV 242
              |...|....:......|:|||||:.|.||.|..:.| |..:|::.|..|..|:|....|:.::
 Frog   183 --IMAVQPALPWDDHKPRITWRGDGQLFAVSSVCKETGNRKIRVWNRELALQSTSESIEGLEQAL 245

  Fly   243 VWRPTGNWIAVPQQFPNKSTIALFEKNGLRHRELVLPFDLQEEPVVQLRWSEDSDILAI------ 301
            .|:|:|..||..|..|||::|...|||||.|.|..|||...::.|.:|.|:.||.:|||
 Frog   246 SWKPSGALIASSQSKPNKNSIIFIEKNGLVHGEFTLPFIKGQKKVKELLWNSDSTVLAIWLEDVE 310

  Fly   302 -----RTCAKEEQRVYLYTIGNYHWYLKQVLIF--EQADPLALLHWDTRCGAEHTLHVLKESGKH 359
                 .:|.     |.|:|:|||||||||.|.|  .:.:.:..|.||..  ..:.||::.....:
 Frog   311 KEGSSSSCC-----VQLWTVGNYHWYLKQNLHFGNNKMNNVECLMWDPE--NAYRLHIICTGWHY 368

  Fly   360 LVYRWAFAVDRNN---SIVGVIDGKRLLLTDFDEAIVPPPMSKIVLKFETYIN------------ 409
            ..:.|.::.|.::   ..|.||||.::|:|.|..|:||||||...::....:|
 Frog   369 FCFDWFWSTDCSDGGQGDVAVIDGDKVLVTSFQHAVVPPPMSTYFIQLSCAVNEVAFQLDPKESS 433

  Fly   410 --AFISHGTSLWVYTCDRKIYLNEHIH---------------------TLGKELQKPIMLMPDAE 451
              |.:....:|.:|.     |.|..::                     .|.|:|:.|
 Frog   434 GLAILDSANTLSIYR-----YGNSTVNDPTVKLEAVGGNGFKTSYKTPKLEKKLRLP-------- 485

  Fly   452 LSGLHLANLTHFSPHYLLATHSSAGSTRLLLLSYKDNDNKPGEWFYRV----HSSVRINGLVNAV 512
                  :||....|            ....||::..:|.     |..:    :||:.|...:.|.
 Frog   486 ------SNLCDVQP------------LNFRLLTWVQDDT-----FIAISQEPNSSISIVHQMTAD 527

  Fly   513 AVAPYAMNEFYVQTVNNGHTYEVSLKAD-KTLKVERSYVQL-----HEPADQID-WVIVKG---- 566
            .:....:|...|.|: .||...:...:: |...::.|..||     ..|...:: |:...|
 Frog   528 QMDGQDINVRDVGTI-TGHVISLCYSSNTKHCAIQTSNGQLWKYLWENPTPVVEPWIDGMGHKVK 591

  Fly   567 ----CIWDGYTG-----ALVTLRNQHLLHIDGYRIGEDVTSFCVVTNYLVY-TQLNAMHFVQLDD 621
                |:....|.     .::.|..:..|.|:...:..::|||.:...:|:. |..:....|.|.|
 Frog   592 FPQPCLQTALTSIEGEEVVIGLTERSRLFINSSEVASNITSFHLYKEFLLLTTHSHTCRCVSLQD 656

  Fly   622 ------RRQVAS---------RNIERGAKIVTAVARKARVVLQLPRGNLEAICPRVLVLELVGDL 671
                  ..|:.|         |.:|||::|||.|....:::||:||||||.:..|.|||..:...
 Frog   657 TSLKALEAQLNSTSNPNDETIRKVERGSRIVTVVPFDTKLILQMPRGNLETVHHRALVLAQIRKW 721

  Fly   672 LERGKYQKAIEMSRKQRINLNIIFDHDVKRFVSSVGAFLNDINEPQWLCLFLSELQNEDFTKGMY 736
            |:...:::|.|..||.|||||:::||:.|.|:.:|..|:..|....::.|||:|:::||.||.||
 Frog   722 LDSLLFKEAFECMRKLRINLNLLYDHNPKAFLDNVDLFITQIGSVNYINLFLTEIKDEDVTKTMY 786

  Fly   737 SSNYDASKQTYPSDYRVD-QKVEYVCRLLEQQMNRF-VSRFRLPLITAYVKLGC--LEMALQVIW 797
            ::   ||..|..|..... :||:.:|..:...|.:. ..:|.|.::|:||:...  ||:|||.:
 Frog   787 AT---ASLITMQSSQGAKAKKVDIICDAVRTAMEKLDPQKFCLSILTSYVRKTKPELEIALQKV- 847

  Fly   798 KEQQEDASL----ADQLLQHLLYLVDVNDLYNVALGTYDFGLVLFVAQKSQKDPKEFLPYLNDLK 858
            .|.:|..|.    ||:.|::||:|||||:||:.:||||||.||:.||:||||||||:||:||.||
 Frog   848 HELRESPSTTVVSADEALKYLLFLVDVNELYDYSLGTYDFDLVVMVAEKSQKDPKEYLPFLNKLK 912

  Fly   859 ALPIDYRKFRIDDHLKRYTSALSHLAACGEQHYEEALEYIRKHGLYTDGLAFYREHIEFQKNIYV 923
            .:.|:|:::.||.|||||..||.:|:.||..::.|.|..::...|||:.|..|:......|.|..
 Frog   913 KMEINYQRYTIDKHLKRYRKALRNLSKCGSGYFAEFLNLVKDQNLYTEALELYQHGTVEYKAINA 977

  Fly   924 AYADHLRAIAKLDNASLMYERGGQLQQALLSAKHTLDWQRVLVLAKKL---SEPLDQVAQSLVGP 985
            ||.|||.:..:.:.|.|:|.|....::||.:...:.:|.:|:.:|.:|   .|.:..:|:::.|.
 Frog   978 AYGDHLVSKQQYELAGLIYARCDSTEKALDAFVASSNWHQVMCMASQLEYSGEKIAALARTVAGK 1042

  Fly   986 LQQQGRHMEAYELVKEHCQDRKRQFDVLLEGHLYS---RAIYEAGLEDDDVSE-KIAPALLAYGV 1046
            |.:|.:..:|..|::::.:|.:....:||:|..:.   |.||:  .:..|:.| .:.||||  ..
 Frog  1043 LLEQRKQADAAVLLEQYAEDYEEAILLLLDGAHWEEALRLIYK--YKRLDILETNLKPALL--DA 1103

  Fly  1047 QLESSLQADLQ--LFLDYKQRLLDIRRNQAKSGEGYIDTDV-NLKEVDLLSDTTSL-----HSSQ 1103
            |....:..:.|  .|..:|:||..:|..:.|:.:|.:|.|: ...|.||.|:|:|:     .|.:
 Frog  1104 QRNHMILFENQKTTFTRHKERLSVVREMKEKARQGLLDEDMTGCAEADLFSETSSIMTASNASGK 1168

  Fly  1104 YSGTSRRTGKTFRSSKNRRKHERKLFSLKPGNPFEDIALIDALHNHVTKIAQQQQPVRDTCKALL 1168
            ||.::.|...  ||||||||.|||..|||.|:|.||:||::||..::..:.:.:..|....|.|:
 Frog  1169 YSQSNSRISS--RSSKNRRKAERKKHSLKEGSPLEDLALLEALAENIKMVDKLRGDVHSLLKVLI 1231

  Fly  1169 QLANAADADPLAAALQREFKTLLQAVDAALDEIWTPELRGNGLMADHLTGPN 1220
            ..    :.|.:|..||:.:..|||..:.::.:||.|.::.|  .|..:.||:
 Frog  1232 LF----EYDTMAKELQQAYDDLLQLFETSILDIWPPGVQQN--TAAPILGPH 1277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elp1	NP_001262478.1	IKI3	1..887	CDD:428111	318/1002 (32%)
elp1	XP_012812382.1	IKI3	1..941	CDD:428111	318/1002 (32%)
		SNAP	924..>1082	CDD:451671	46/157 (29%)
		TPR repeat	957..998	CDD:276937	15/40 (38%)
		TPR repeat	1002..1039	CDD:276937	8/36 (22%)
		TPR repeat	1040..1076	CDD:276937	9/35 (26%)