Protein Alignment Csk and AT1G73660

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_177507.1
• Gene: AT1G73660 / 843701
• AraportID: AT1G73660
• Length: 1030
• Species: Arabidopsis thaliana
• Alignment Length: 692
• Identity: 162/692 - (23%)
• Similarity: 270/692 - (39%)
• Gaps: 176/692 - (25%)

  Fly   405 SSGTAPGSAVGAVLLHQQQLSQSQPHIVPPSIPPHHHHHRENNVHPIQAGAAAALHLSSHALNSH 469
            |||....|..|..|            ||.|:|      .||:..:..:...|...:|||..::|.
plant   439 SSGERNQSGGGGDL------------IVHPNI------SREDVKNQKKVEKAPFQNLSSRPIHSF 485

  Fly   470 NLISSAS-NHSPKSPSQTQQQQQTTNQ------QQQQQQQQASHSIL---STFAPAPTVAAVQPA 524
            ..:.|.| .....||:..:.:.:..:|      ::..:..|..|.:|   ...||....:.|.|
plant   486 THMRSPSWTEGVSSPAAQRMKVKDVSQYMIDAAKENPRLAQKLHDVLLESGVVAPPNLFSEVYP- 549

  Fly   525 GSQSVAGTAAAVAAVAQQQQQQHLQLLANCPPGGAGLMSSSLNAAQMGMH----GAERALPP--- 582
              |.:..|..:..:...::::                 ...|...|.|.|    |..|.|||
plant   550 --QQLEATVESKNSTEAKKER-----------------GKDLETTQEGRHQNGFGPVRFLPPLPR 595

  Fly   583 --------------KSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMSTSLHSFDI 633
                          |.::.|.|.|........|...|.|...||||..|...:|
plant   596 VQSKTNAHDQRDNGKVVSQSDSSHSEASSTEYARTVPAAVAAAAVVASSMVAAA----------- 649

  Fly   634 NGVTAGSGVNASS------AWSSGSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRD 692
                |....|:.|      |.::.:.||   |::..||.|..:   :.|:..|:        ..|
plant   650 ----AAKSANSDSSPIELPAAAAATATA---AAVVATAAAVSR---QLELGSNS--------DGD 696

  Fly   693 EAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAH 757
            :.....:|:..|     :|.:.|         .|..|....|.:.|:.:..|
plant   697 DGSGGHEPQGSG-----DSNHGP---------NSGGERISDKSIGNESSKSD------------- 734

  Fly   758 YEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNE 822
                    |..:..|                 :..|    .|:.:.|.||.|.:|:|..|.....
plant   735 --------CDDVSDC-----------------EILW----EEITVGERIGLGSYGEVYRGDWHGT 770

  Fly   823 KVAVKMLKDEG----AVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLR 883
            :||||...|:.    |:::|.:|..:|..|.|.|:|.|:|.|....:|.:|||::.:|||...:.
plant   771 EVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLFMGAVTRPPNLSIVTEFLPRGSLYRLIH 835

  Fly   884 SRGRQHITKKDQIIFAYDTASGMEYLEA--KKVVHRDLAARNVLISEDCVAKVSDFGLAREECYN 946
             |....:.::.::..|.|.|.||.||.:  ..:|||||.:.|:|:.::.|.||.||||:|.:...
plant   836 -RPNNQLDERRRLRMALDAARGMNYLHSCNPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHST 899

  Fly   947 LDVGKL---PIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGY- 1007
            ....|.   ..:|.|||.|:|.....|.|::|:|::|||:::. :.|:.::....||.  .||:
plant   900 YLSSKSTAGTAEWMAPEVLRNEPADEKCDVYSYGVILWELFTL-QQPWGKMNPMQVVG--AVGFQ 961

  Fly  1008 --KMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL 1047
              :::.|:...|.|.:::.:.|..:...||:|||:...|:.|
plant   962 HRRLDIPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKRL 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	13/96 (14%)
		PTKc_Csk_like	793..1047	CDD:270635	84/265 (32%)
AT1G73660	NP_177507.1	EDR1	178..382	CDD:433922
		STKc_MAP3K-like	754..1000	CDD:270901	80/249 (32%)