DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csk and AT1G49730

DIOPT Version :9

Sequence 1:	NP_001262476.1	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_849788.2	Gene:	AT1G49730 / 841396	AraportID:	AT1G49730	Length:	693	Species:	Arabidopsis thaliana

Alignment Length:	278	Identity:	82/278 - (29%)
Similarity:	129/278 - (46%)	Gaps:	48/278 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   806 IGKGEFGDVMLGILRNEKVAV--KMLK-DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLY 867
            ||:|.||.|......:..:|.  ||.| .|.|.|.|..|..::..|.|.|||...|.....|..:
plant   363 IGQGGFGTVYKAEFNDGLIAAVKKMNKVSEQAEQDFCREIGLLAKLHHRNLVALKGFCINKKERF 427

  Fly   868 LVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLE---AKKVVHRDLAARNVLISED 929
            ||.:||..|||.|:|.:.|:...:...::..|.|.|:.:|||.   ...:.|||:.:.|:|:.|:
plant   428 LVYDYMKNGSLKDHLHAIGKPPPSWGTRMKIAIDVANALEYLHFYCDPPLCHRDIKSSNILLDEN 492

  Fly   930 CVAKVSDFGLAREE-----CY---NLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSF 986
            .|||:||||||...     |:   |.|:...| .:..||.:.....:.|||::|:|::|.|:.:
plant   493 FVAKLSDFGLAHSSRDGSVCFEPVNTDIRGTP-GYVDPEYVVTQELTEKSDVYSYGVVLLELIT- 555

  Fly   987 GR---------VPYPRIPLADVVKHVEV-------------GYKMEAPEGCPPEIYEMMRQAWDL 1029
            ||         |...:..|....||:|:             |.:::|       :..::|...:.
plant   556 GRRAVDEGRNLVEMSQRFLLAKSKHLELVDPRIKDSINDAGGKQLDA-------VVTVVRLCTEK 613

  Fly  1030 NPAKRPTFAELKVKLQLL 1047
            ....||:   :|..|:||
plant   614 EGRSRPS---IKQVLRLL 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190
		PTKc_Csk_like	793..1047	CDD:270635	80/276 (29%)
		STYKc	800..1044	CDD:214568	79/273 (29%)
AT1G49730	NP_849788.2	S_TKc	362..626	CDD:214567	79/274 (29%)
AT1G49730	NP_849788.2	STKc_IRAK	363..630	CDD:270968	82/278 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1899
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050