Protein Alignment Csk and CTR1

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_195993.1
• Gene: CTR1 / 831748
• AraportID: AT5G03730
• Length: 821
• Species: Arabidopsis thaliana
• Alignment Length: 920
• Identity: 198/920 - (21%)
• Similarity: 318/920 - (34%)
• Gaps: 296/920 - (32%)

  Fly   266 FDEEAQARKTSHEKSQKPKPKPE------------------ENHKEKEAISRKASGEGDLITVEI 312
            :|..:...:::|......|.|.|                  .|...:...:..||..|
plant    33 YDSLSSENRSNHNSGNTGKAKAERGGFDWDPSGGGGGDHRLNNQPNRVGNNMYASSLG------- 90

  Fly   313 KQGLLRKQTATTTTGQAMNS------HATATQNGQTTV---------VGHHRGFSQPSVTVAAAA 362
                |::|::.::.|::..|      ..:|..|...:|         :|...|.....:.:||.:
plant    91 ----LQRQSSGSSFGESSLSGDYYMPTLSAAANEIESVGFPQDDGFRLGFGGGGGDLRIQMAADS 151

  Fly   363 ATGSTAGDPWFLQT-TGHQMPPTAPLRHNKR-----------PAPQPNAVLGAGSSGTAPGSA-- 413
            |.||::|..|..|| ..:|:.....||.:..           |.|..:|:      .|:|.||
plant   152 AGGSSSGKSWAQQTEESYQLQLALALRLSSEATCADDPNFLDPVPDESAL------RTSPSSAET 210

  Fly   414 ------VGAVLLHQQQLSQSQPHIVPPSIPPHHHHHRENNVHPIQAGAAAALHLSSH--ALNSHN 470
                  |...|.:..:        ||...      :..|.:.|........||.|..  ::.|..
plant   211 VSHRFWVNGCLSYYDK--------VPDGF------YMMNGLDPYIWTLCIDLHESGRIPSIESLR 261

  Fly   471 LISSASNHSPKSPSQTQQQQQTTNQQQQQQQQQASHSILSTFAPAPTVA---------------- 519
            .:.|..:.|.:: ....::.....::...:....|.|.::|......:|
plant   262 AVDSGVDSSLEA-IIVDRRSDPAFKELHNRVHDISCSCITTKEVVDQLAKLICNRMGGPVIMGED 325

  Fly   520 ------------------AVQPAGSQSV-------------AGTAAAVAAVAQQQQQQHLQLLAN 553
                              .|.|.||.||             |........:|:..:..:....|:
plant   326 ELVPMWKECIDGLKEIFKVVVPIGSLSVGLCRHRALLFKVLADIIDLPCRIAKGCKYCNRDDAAS 390

  Fly   554 C----------------PPGGAGLMSSSLNAAQMGMHGAERALPPKSLALSGSQHGSNMLLHTAP 602
            |                .||......|.||.             |.|:::      |:.|....|
plant   391 CLVRFGLDREYLVDLVGKPGHLWEPDSLLNG-------------PSSISI------SSPLRFPRP 436

  Fly   603 QPPQA--------------SQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGVNASSAWSSGST 653
            :|.:.              ||...:|....|...|.|.....:|..|     |.|.:.|.:.|
plant   437 KPVEPAVDFRLLAKQYFSDSQSLNLVFDPASDDMGFSMFHRQYDNPG-----GENDALAENGG-- 494

  Fly   654 TAMNHASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDY 718
                 .||.|:|..|.|...|...::.|.|.        .|..:.||
plant   495 -----GSLPPSANMPPQNMMRASNQIEAAPM--------NAPPISQP------------------ 528

  Fly   719 TLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCI 783
                             :.|:                |:.|...||
plant   529 -----------------VPNR----------------ANRELGLDG------------------- 541

  Fly   784 NSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLKDEG----AVQKFLAEASV 844
               |.:|    ||..:|.::|.||.|.||.|.........||||:|.::.    .|.:||.|.::
plant   542 ---DDMD----IPWCDLNIKEKIGAGSFGTVHRAEWHGSDVAVKILMEQDFHAERVNEFLREVAI 599

  Fly   845 MTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRG-RQHITKKDQIIFAYDTASGMEY 908
            |..|.|.|:|.|:|.|....:|.:||||:|:|||...|...| |:.:.::.::..|||.|.||.|
plant   600 MKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNY 664

  Fly   909 LEAKK--VVHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGKLPI---KWTAPEALKNGRFS 968
            |..:.  :|||||.:.|:|:.:....||.||||:|.:.......|...   :|.|||.|::...:
plant   665 LHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSN 729

  Fly   969 NKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYK---MEAPEGCPPEIYEMMRQAWDLN 1030
            .|||::|||::|||:.:. :.|:..:..|.||  ..||:|   :|.|....|::..::...|...
plant   730 EKSDVYSFGVILWELATL-QQPWGNLNPAQVV--AAVGFKCKRLEIPRNLNPQVAAIIEGCWTNE 791

  Fly  1031 PAKRPTFAEL 1040
            |.|||:||.:
plant   792 PWKRPSFATI 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	10/96 (10%)
		PTKc_Csk_like	793..1047	CDD:270635	93/261 (36%)
CTR1	NP_195993.1	EDR1	207..412	CDD:433922	30/219 (14%)
		STKc_MAP3K-like	557..805	CDD:270901	89/248 (36%)