DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csk and CRK13

DIOPT Version :9

Sequence 1:	NP_001262476.1	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001078435.1	Gene:	CRK13 / 828420	AraportID:	AT4G23210	Length:	673	Species:	Arabidopsis thaliana

Alignment Length:	236	Identity:	76/236 - (32%)
Similarity:	114/236 - (48%)	Gaps:	24/236 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   795 IPEAELQLRESIGKGEFGDVMLGILRNEK-VAVKML--KDEGAVQKFLAEASVMTTLEHDNLVKF 856
            |..|.....|.:|.|..|.|..|.|.:.| :|||.|  |.|.:.::|..|..::..|:|.|||:.
plant   353 IETATNNFSERLGHGGSGHVFKGRLPDGKEIAVKRLSEKTEQSKKEFKNEVVLVAKLQHRNLVRL 417

  Fly   857 IGLVFTSKHLYLVTEYMSKGSLVDYL----RSRGRQHITKKDQIIFAYDTASGMEYLEAKK---V 914
            :|.....:...:|.||:...|| ||:    ..:|.....|:.:||..  ||.|:.||....   :
plant   418 LGFSVKGEEKIIVYEYLPNRSL-DYILFDPTKQGELDWKKRYKIIGG--TARGILYLHQDSQPTI 479

  Fly   915 VHRDLAARNVLISEDCVAKVSDFGLAREECYNLD--------VGKLPIKWTAPEALKNGRFSNKS 971
            :||||.|.|:|:......||:|||.||  .:.:|        ....| .:.|||.::.|.||.||
plant   480 IHRDLKAGNILLDAHMNPKVADFGTAR--IFGMDQSVAITANAAGTP-GYMAPEYMELGEFSMKS 541

  Fly   972 DMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAP 1012
            |::|:|:|:.||....|......|:.:.|.:|...:|...|
plant   542 DVYSYGVLVLEIICGKRNTSFSSPVQNFVTYVWRLWKSGTP 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190
		PTKc_Csk_like	793..1047	CDD:270635	76/236 (32%)
		STYKc	800..1044	CDD:214568	74/231 (32%)
CRK13	NP_001078435.1	Stress-antifung	26..124	CDD:396296
		Stress-antifung	<175..245	CDD:396296
		STKc_IRAK	364..628	CDD:270968	73/225 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000