DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Csk and CERK1

DIOPT Version :9

Sequence 1:	NP_001262476.1	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_566689.2	Gene:	CERK1 / 821717	AraportID:	AT3G21630	Length:	617	Species:	Arabidopsis thaliana

Alignment Length:	325	Identity:	97/325 - (29%)
Similarity:	141/325 - (43%)	Gaps:	93/325 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   789 VDKGWVIPEAELQLRE------------SIGKGEFGDVMLGILRNEKVAVKMLKDEGAVQKFLAE 841
            |||     ..|..|.|            .||:|.||.|....||.||.|:|.: |..|.::||||
plant   304 VDK-----SVEFSLEELAKATDNFNLSFKIGQGGFGAVYYAELRGEKAAIKKM-DMEASKQFLAE 362

  Fly   842 ASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHI--TKKDQIIFAYDTAS 904
            ..|:|.:.|.|||:.||...... |:||.||:..|:|..:|...||:.:  ||:.||  |.|:|.
plant   363 LKVLTRVHHVNLVRLIGYCVEGS-LFLVYEYVENGNLGQHLHGSGREPLPWTKRVQI--ALDSAR 424

  Fly   905 GMEYLEAKKV---VHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGKLPIK-------WTAP 959
            |:||:....|   ||||:.:.|:||.:...|||:||||.:    ..:||....:       :.||
plant   425 GLEYIHEHTVPVYVHRDIKSANILIDQKFRAKVADFGLTK----LTEVGGSATRGAMGTFGYMAP 485

  Fly   960 EALKNGRFSNKSDMWSFGILLWEIYS----------------------------------FGRVP 990
            |.: .|..|.|.|:::||::|:|:.|                                  ..::.
plant   486 ETV-YGEVSAKVDVYAFGVVLYELISAKGAVVKMTEAVGEFRGLVGVFEESFKETDKEEALRKII 549

  Fly   991 YPRI----PLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLNNAT 1051
            .||:    |...|.|..|:|      :.|..|           |...||:...:.|.|..|.::|
plant   550 DPRLGDSYPFDSVYKMAELG------KACTQE-----------NAQLRPSMRYIVVALSTLFSST 597

Fly 1052 1051
plant 598 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190
		PTKc_Csk_like	793..1047	CDD:270635	92/315 (29%)
		STYKc	800..1044	CDD:214568	90/305 (30%)
CERK1	NP_566689.2	mltD	<104..202	CDD:182727
CERK1	NP_566689.2	PKc_like	328..587	CDD:419665	87/284 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1899
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050