DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Csk and LYK5

DIOPT Version :9

Sequence 1:	NP_001262476.1	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_180916.1	Gene:	LYK5 / 817923	AraportID:	AT2G33580	Length:	664	Species:	Arabidopsis thaliana

Alignment Length:	695	Identity:	147/695 - (21%)
Similarity:	251/695 - (36%)	Gaps:	202/695 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   482 SPSQTQQQQQTTNQQQQQQQQQASHSILSTFA--PAPTVAAVQPAGSQSVAGTAAAVAAVAQQQQ 544
            ||::.||..  .|..|...:.:...:|.:.|.  ..|:..:.....||....||.::|.:.....
plant    22 SPAKAQQPY--VNNHQLACEVRVYDNITNGFTCNGPPSCRSYLTFWSQPPYNTADSIAKLLNVSA 84

  Fly   545 QQHLQLLANCP--------------PGGAGLMSSSLNAAQ-------MGMHGAE----------R 578
            .: :|.:.|.|              |......|||....|       .|..|.|          :
plant    85 AE-IQSINNLPTATTRIPTRELVVIPANCSCSSSSGGFYQHNATYNLSGNRGDETYFSVANDTYQ 148

  Fly   579 ALPPKSLALSGSQHGS-------NMLLHTAPQPPQASQPAA----------VVGVSGSGSAGMST 626
            ||......:|.:::|.       |:|:......|.|.|..|          .:|.|.||.|.|..
plant   149 ALSTCQAMMSQNRYGERQLTPGLNLLVPLRCACPTAKQTTAGFKYLLTYLVAMGDSISGIAEMFN 213

  Fly   627 SLHSFDINGVTAGSGVNASSAWSSGS-----TTAMNHASLSPT-------ALAPQ-----QGRSR 674
            |..:    .:|.|:.:.:.:.:....     ||......:||:       |..||     .|.|
plant   214 STSA----AITEGNELTSDNIFFFTPVLVPLTTEPTKIVISPSPPPPPVVATPPQTPVDPPGSS- 273

  Fly   675 CEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENK 739
                 ::..|.:..|....          ||.|:..        .|.:||..:  ..:.|.|.:.
plant   274 -----SSHKWIYIGIGIGA----------GLLLLLS--------ILALCFYKR--RSKKKSLPSS 313

  Fly   740 LTIDDEEYFENLGQLV-----------AHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGW 793
            |..:::.:..:..|.:           ....::|.|| ...|:.|......:....:.:|.|:..
plant   314 LPEENKLFDSSTKQSIPTTTTTQWSIDLSNSSEAFGL-KSAIESLTLYRFNDLQSATSNFSDENR 377

  Fly   794 VIPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLKDEGAVQKFLAEASVMTTLEHDNLVKFIG 858
            :                .|.|....:..:..|||::|  |.|..  :|.:::..|.|.|:::..|
plant   378 I----------------KGSVYRATINGDDAAVKVIK--GDVSS--SEINLLKKLNHSNIIRLSG 422

  Fly   859 LVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLE---AKKVVHRDLA 920
            ........|||.||...||:.|:|.|.|::.:|.|.::..|.|.|..::||.   ....:|::|.
plant   423 FCIREGTSYLVFEYSENGSISDWLHSSGKKSLTWKQRVEIARDVAEALDYLHNYITPPHIHKNLE 487

  Fly   921 ARNVLISEDCVAKVSDFGLAREECYNLDVGKLPIKWT----------APEALKNGRFSNKSDMWS 975
            :.|:|:..:..||:::||:||    .||.|.|.::.|          |||.::||..::|.|:::
plant   488 STNILLDSNFRAKIANFGVAR----ILDEGDLDLQLTRHVEGTQGYLAPEYVENGVITSKLDVFA 548

  Fly   976 FGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEG----C--------------------- 1015
            ||:.:.|:.| ||            :.|.:..|.|..|.    |
plant   549 FGVAVLELLS-GR------------EAVTIHKKKEGEEEVEMLCKVINSVLGGENVREKLKEFMD 600

  Fly  1016 -------PPEIYEMMRQ------AWDLNPAKRPTFAELKVKLQLL 1047
                   |.|:...|.|      |.|||  .||:..::...|.::
plant   601 PSLGNEYPLELAYTMAQLAKSCVATDLN--SRPSVTQVLTTLSMI 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	17/107 (16%)
		PTKc_Csk_like	793..1047	CDD:270635	75/304 (25%)
		STYKc	800..1044	CDD:214568	74/294 (25%)
LYK5	NP_180916.1	LysM	197..239	CDD:396179	9/45 (20%)
LYK5	NP_180916.1	PKc_like	380..640	CDD:419665	74/282 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1899
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050