Protein Alignment Csk and STY8

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_179361.1
• Gene: STY8 / 816278
• AraportID: AT2G17700
• Length: 546
• Species: Arabidopsis thaliana
• Alignment Length: 645
• Identity: 146/645 - (22%)
• Similarity: 256/645 - (39%)
• Gaps: 177/645 - (27%)

  Fly   463 SHALNSHNLISSASNHSPKS-------PSQTQQQQQTTNQQQ----------------------- 497
            |.:..|..:::|.|..:|:.       .|:..|:.|.:|.::
plant     7 SESCGSRAVVASPSQENPRHYRMKLDVYSEVLQRLQESNYEEATLPDFEDQLWLHFNRLPARYAL 71

  Fly   498 ----QQQQQQASHSILSTFAPAPTVAAVQPAGSQSVAGTAAAVA--AVAQQQQQQHLQLLANCPP 556
                ::.:...:|..|...|..|....|....|..|:...:|.:  ||.:..|..|       .|
plant    72 DVKVERAEDVLTHQRLLKLAADPATRPVFEVRSVQVSPRISADSDPAVEEDAQSSH-------QP 129

  Fly   557 GGAGLM-------SSSLNAAQMGMHGAERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVV 614
            .|.|::       |.:..|...|....|......:..|| ::....:...|..:|...||..:::
plant   130 SGPGVLAPPTFGSSPNFEAITQGSKIVEDVDSVVNATLS-TRPMHEITFSTIDKPKLLSQLTSLL 193

  Fly   615 GVSG---SGSAGMST----SLHSFDINGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQGR 672
            |..|   ..:...||    ||..|.::|            ||...|..:..| ||...|
plant   194 GELGLNIQEAHAFSTVDGFSLDVFVVDG------------WSQEETDGLRDA-LSKEIL------ 239

  Fly   673 SRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLE 737
                 ||           :|:                     ||.....:.|
plant   240 -----KL-----------KDQ---------------------PGSKQKSISF------------- 254

  Fly   738 NKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQL 802
                      ||        ::..::.|....|: :|..|..|            |.|...:|::
plant   255 ----------FE--------HDKSSNELIPACIE-IPTDGTDE------------WEIDVTQLKI 288

  Fly   803 RESIGKGEFGDVMLGILRNEKVAVKMLKDEGA----VQKFLAEASVMTTLEHDNLVKFIGLVFTS 863
            .:.:..|.:||:..|...:::||:|.||.:..    :::|..|..:|..:.|.|:|:|:|....|
plant   289 EKKVASGSYGDLHRGTYCSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRS 353

  Fly   864 KHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIF--AYDTASGMEYLEAKKVVHRDLAARNVLI 926
            ..|.:|||:|::||:.|:|.   :|....|.|.:.  |.|.|.||.||....::||||...|:|:
plant   354 PTLCIVTEFMARGSIYDFLH---KQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLM 415

  Fly   927 SEDCVAKVSDFGLAREECYNLDVGKL-----PIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSF 986
            .|..:.||:|||:||.:   ::.|.:     ..:|.|||.:::..:::|:|::|:.|:|||:.:
plant   416 DEHGLVKVADFGVARVQ---IESGVMTAETGTYRWMAPEVIEHKPYNHKADVFSYAIVLWELLT- 476

  Fly   987 GRVPYPRI-PLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ 1045
            |.:||..: ||...|..|:.|.:.:.|:...|::..::.:.|..:|.:||.|.|:...||
plant   477 GDIPYAFLTPLQAAVGVVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQ 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	9/96 (9%)
		PTKc_Csk_like	793..1047	CDD:270635	84/265 (32%)
STY8	NP_179361.1	ACT_TyrKc	172..239	CDD:153200	18/79 (23%)
		STKc_MAP3K-like	292..535	CDD:270901	79/249 (32%)