DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Csk and SERK5

DIOPT Version :9

Sequence 1:	NP_001262476.1	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001318220.1	Gene:	SERK5 / 815863	AraportID:	AT2G13800	Length:	601	Species:	Arabidopsis thaliana

Alignment Length:	583	Identity:	135/583 - (23%)
Similarity:	218/583 - (37%)	Gaps:	182/583 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 GSQSVAGTAAAVAAVAQQQQQQHLQLLANCPPG-------------GAGLMSSSLNA---AQMGM 573
            ||.:::|  ..|..:||....|:|:|..|...|             ...|.:::::.   :.:|.
plant    78 GSANLSG--ELVPQLAQLPNLQYLELFNNNITGEIPEELGDLMELVSLDLFANNISGPIPSSLGK 140

  Fly   574 HGAERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMSTSLHSFDINGVTA 638
            .|..|.|...:.:|||....|...|           |..|:.:|.:..:|      ...:||
plant   141 LGKLRFLRLYNNSLSGEIPRSLTAL-----------PLDVLDISNNRLSG------DIPVNG--- 185

  Fly   639 GSGVNASSAWSSGSTTAMNHAS--LSPTALAPQ---QGRSRCEV--------KLNAMPWFHGSIT 690
                      |....|:|:.|:  |.|...:|.   .|.|...|        .|.|:.|:
plant   186 ----------SFSQFTSMSFANNKLRPRPASPSPSPSGTSAAIVVGVAAGAALLFALAWW----- 235

  Fly   691 RDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTIDDEEYFENLGQLV 755
                   |:.:..|.||     :.|.:                         :|.|.:  |||.
plant   236 -------LRRKLQGHFL-----DVPAE-------------------------EDPEVY--LGQF- 260

  Fly   756 AHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILR 820
                                          |.|..:..::...:...|..:|||.||.:..|.|.
plant   261 ------------------------------KRFSLRELLVATEKFSKRNVLGKGRFGILYKGRLA 295

  Fly   821 NEK-VAVKMLKDE---GAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDY 881
            ::. ||||.|.:|   |...:|..|..:::...|.||::..|...|.....||..||:.||:...
plant   296 DDTLVAVKRLNEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASC 360

  Fly   882 LRSR----------GRQHITKKDQIIFAYDTASGMEYLE---AKKVVHRDLAARNVLISEDCVAK 933
            ||.|          .|:||        |..:|.|:.||.   .:|::|.|:.|.|:|:.|:..|.
plant   361 LRERPEGNPALDWPKRKHI--------ALGSARGLAYLHDHCDQKIIHLDVKAANILLDEEFEAV 417

  Fly   934 VSDFGLAREECYNLDVGKLPIKWT----APEALKNGRFSNKSDMWSFGILLWEI------YSFGR 988
            |.|||||:...||.......::.|    |||.|..|:.|.|:|::.:|::|.|:      :...|
plant   418 VGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQKAFDLAR 482

  Fly   989 VPY-PRIPLADVVKHVEVGYKMEA-----PEG--CPPEIYEMMRQA---WDLNPAKRPTFAEL 1040
            :.. ..|.|.|.||.|....|:|:     .||  ...|:.::::.|   ...:..:||..:|:
plant   483 LANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQMALLCTQSSAMERPKMSEV 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	12/96 (13%)
		PTKc_Csk_like	793..1047	CDD:270635	83/286 (29%)
		STYKc	800..1044	CDD:214568	83/279 (30%)
SERK5	NP_001318220.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1899
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050