Protein Alignment Csk and Cad96Ca

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Alignment Length: 989
• Identity: 230/989 - (23%)
• Similarity: 345/989 - (34%)
• Gaps: 323/989 - (32%)

  Fly   132 HKEASTHATHTGGQVISRARRKPILLCSSLSAAYAPPRRREFYFCDKYAPGPARSTPTTTTTSAT 196
            |....:...|...|:.|..||..:|....::|                       |..:..:...
  Fly     5 HHNHESRIIHCRKQLTSWRRRSLLLTIIVVTA-----------------------TVVSLISQEA 46

  Fly   197 SAKHESSPPIDARLLNFLRCAHRKFQASKAKTELQQTKDRFLGNSRERTSKNGQQTSRSLPPIAS 261
            .|.::::|||       |....|.::.|:                   |.|.||...|.......
  Fly    47 EAHNQNAPPI-------LYVRERNWRISE-------------------TEKVGQIIDRVRAEDPD 85

  Fly   262 SEEW-FDEEAQARKTSHEKSQKPKPK-PEENHKE------KEAISRKASGEGDLITVEIKQG--L 316
            .::. |..|.:......|....|..| |.:..:|      .|:::.:| |:..||.:.:..|  .
  Fly    86 GDDLIFGIEPRFSLPGGENDASPPEKIPFQIDRETGVVTLNESLAGRA-GQNFLIYITVTDGSYT 149

  Fly   317 LRKQTATTTTGQAMNSHATATQNGQTTVVGHHRGF-----SQPSVTVAAAAATGSTAGDPWFLQT 376
            .:.:......|:..||.....|...:.||.:...|     ..|.|.........|..|. |:
  Fly   150 AKNEVFINILGERENSSGYRPQTSISNVVHNISQFLPRFDQLPGVQSIRNGLPNSRPGG-WY--- 210

  Fly   377 TGHQMPPT-------APLRHNKRPAPQPNAVLGAGSSGTAPGSAVGAVLLHQQQLSQSQP-HIVP 433
                 ||.       .|...|..|.|.||          .||      :..:|...:.|| ..|.
  Fly   211 -----PPVPQNNIFGPPPFGNNYPPPPPN----------IPG------VRGEQSGEEEQPDEEVT 254

  Fly   434 PSIPPHHHHHRENNVHPIQAGAAAALHLSSHALNSH-NLISSASNHSPKSPSQTQQQQQTTNQQQ 497
            |:.|                     :.:||....|. .|....:|:|.:..|....:..|.:...
  Fly   255 PTTP---------------------VRISSTTPKSRTKLTPITANNSTRVESAIPAETTTPSGGH 298

  Fly   498 QQQQQQASHSILSTFA-PAPTVAAVQPAGSQSVAGTAAAVAAVAQQ------------QQQQHLQ 549
            ...    |.|.::.|: .:.|:..|...|...|| .|..:|.:.::            ::::.|.
  Fly   299 HNN----SSSPITIFSLKSGTIPIVVTVGGFFVA-IAVLLAYLCRRRLCAISRTLKKTKEKEELA 358

  Fly   550 LLANCPPGGAGLMSSSLNAAQMGM-HG----AERALP---PKSLALSGSQHGSNMLLHTAPQPPQ 606
            ..:|.....:.|...|.|:..|.. .|    |.|.:|   .:.:.::.||      |.|......
  Fly   359 KKSNQSQLSSTLTDDSRNSMVMQQWQGPVAFANRYVPWERDQQMGIATSQ------LSTGVTNGG 417

  Fly   607 ASQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQG 671
            .|.|    ||...|:....::|          |.|.....|.|||               ||:
  Fly   418 VSSP----GVPSPGTGEPGSNL----------GPGCLTGGAGSSG---------------APE-- 451

  Fly   672 RSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYL 736
                    ||                                |.|
  Fly   452 --------NA--------------------------------FAG-------------------- 456

  Fly   737 ENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQ 801
                                  ||:.|                            .|..|...|:
  Fly   457 ----------------------EANCD----------------------------RWEFPRYRLK 471

  Fly   802 LRESIGKGEFGDV----MLGILRNE---KVAVKMLKDEGAV---QKFLAEASVMTTLE-HDNLVK 855
            ....:|:|.||.|    ...|..||   .||||.||:....   :..|:|..||.:|| |.|:|.
  Fly   472 FFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVVH 536

  Fly   856 FIGLVFTSKHLYLVTEYMSKGSLVDYLR-SRGRQH----------ITKKDQIIFAYDTASGMEYL 909
            .:|........:::.||:::|.|..||| ||..:|          :|..|...|.|..|.||:||
  Fly   537 LLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYL 601

  Fly   910 EAKKVVHRDLAARNVLISEDCVAKVSDFGLARE----ECY-NLDVGKLPIKWTAPEALKNGRFSN 969
            .::.::||||||||:||::|...||:|||.||:    :.| ....|||||:|.|.|:|.:..||.
  Fly   602 TSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFSV 666

  Fly   970 KSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKR 1034
            |||:||||||:|||.:.|..|||.|..|||::.|..||::|.||.|..|:|.:|...|..:|.:|
  Fly   667 KSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQER 731

  Fly  1035 PTFAELKVKLQLLN 1048
            |.|||:   :|:|:
  Fly   732 PLFAEI---IQMLD 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	7/96 (7%)
		PTKc_Csk_like	793..1047	CDD:270635	114/280 (41%)
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637	20/118 (17%)
		PTKc	474..742	CDD:270623	111/270 (41%)