Protein Alignment Csk and ripk2

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_919392.3
• Gene: ripk2 / 373874
• ZFINID: ZDB-GENE-030902-3
• Length: 584
• Species: Danio rerio
• Alignment Length: 306
• Identity: 75/306 - (24%)
• Similarity: 131/306 - (42%)
• Gaps: 56/306 - (18%)

  Fly   782 CINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNEK--VAVKMLKDEGAVQK-----FL 839
            |:|.........|||..:|.....|.||.||.|......:.:  ||:|.||.:..|.:     .|
Zfish    10 CVNICSLTSTLPVIPYRKLTDLHYISKGGFGTVFRAQHSDWRTTVAIKCLKLDSPVGERERNCLL 74

  Fly   840 AEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKD---------Q 895
            .||.|:.....:::::..|:....:...::||||:.|||.:.|.        :||         :
Zfish    75 KEAEVLHKARFNHIIQIFGVCNEPEFFCIITEYMTNGSLDELLH--------EKDIYPAVAWPLR 131

  Fly   896 IIFAYDTASGMEYLE--AKKVVHRDLAARNVLISEDCVAKVSDFGLA--REECYNLDVGKLP--- 953
            :...|:.|.|:.:|.  :..::|.||..:|:|:..:...|::||||:  |:.......|..|
Zfish   132 LRILYEIALGVNFLHNMSPPLLHHDLKTQNILMDGEYHVKIADFGLSKWRQLSITKGSGSKPAEM 196

  Fly   954 ---IKWTAPEAL---KNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKM--- 1009
               :.:..||..   |..|...|.||:|:.|::||:.|      .|||..:....:::.:.:
Zfish   197 GGTVIYMPPEEYEPSKTRRTDVKYDMYSYAIIMWEVLS------RRIPFEEATNPMQIMFSVLRG 255

  Fly  1010 --------EAPEGCPPE--IYEMMRQAWDLNPAKRPTFAELKVKLQ 1045
                    ..|...|..  :..:|...|..||.:||:|....::|:
Zfish   256 ARPDTGLDSLPVDIPSRETLINLMTSGWTANPDERPSFLHCLIELE 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190
		PTKc_Csk_like	793..1047	CDD:270635	73/295 (25%)
ripk2	NP_919392.3	None