Protein Alignment Csk and drk

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Alignment Length: 147
• Identity: 40/147 - (27%)
• Similarity: 66/147 - (44%)
• Gaps: 28/147 - (19%)

  Fly   677 VKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLT 741
            :::....|::|.|||.:||.||..:.:|.||:|.|.:.|||::|.|.....|:|::|
  Fly    53 IEMKNHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKV-------- 109

  Fly   742 IDDEE--------YFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEA 798
            :.|.:        .|.:|.:|| .|...|....:|.:|....:.::.......|||.:    ...
  Fly   110 LRDAQSKFFLWVVKFNSLNELV-EYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQ----ESG 169

  Fly   799 ELQLRESIGKGEFGDVM 815
            ||..|.       |||:
  Fly   170 ELDFRR-------GDVI 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	31/104 (30%)
		PTKc_Csk_like	793..1047	CDD:270635	6/23 (26%)
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	40/147 (27%)
		SH2_Grb2_like	56..149	CDD:199828	31/101 (31%)
		SH3_GRB2_like_C	156..208	CDD:212739	9/35 (26%)