Protein Alignment Csk and Itk

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001102295.2
• Gene: Itk / 363577
• RGDID: 1311618
• Length: 620
• Species: Rattus norvegicus
• Alignment Length: 415
• Identity: 142/415 - (34%)
• Similarity: 221/415 - (53%)
• Gaps: 47/415 - (11%)

  Fly   658 HASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEH-LLQPREDGLFLVRESTNFPGDYTLC 721
            |...:|::...::..:    .|....|::.||:||:||. ||...::|.|:||:|.. ||.||:.
  Rat   217 HEGYAPSSYLVEKSPN----SLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRT-PGTYTVS 276

  Fly   722 V-----------CFQSKVEHYRVKYLEN---KLTIDDEEYFENLGQLVAHYEADADGLCTQLIKC 772
            |           |    ::||.:|...:   :..:.::..|:::..|:.:::.:..||.|:|
  Rat   277 VFTKAIISENNPC----IKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRL--- 334

  Fly   773 LPKLGKQEFCI-NSKDFVDKG-----WVIPEAELQLRESIGKGEFGDVMLGI-LRNEKVAVKMLK 830
                 :...|. ..|..|..|     |||..:||...:.||.|:||.|.||. |..:|||:|.::
  Rat   335 -----RYPVCSWRQKAPVTAGLRYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQ 394

  Fly   831 DEGAV--QKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKK 893
             |||:  :.|:.||.||..|.|..||:..|:......:.||.|:|..|.|.|||||: |.....:
  Rat   395 -EGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQ-RGLFAAE 457

  Fly   894 DQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAR---EECYNLDVG-KLPI 954
            ..:....|...||.|||...|:||||||||.|:.|:.|.||||||:.|   ::.|....| |.|:
  Rat   458 TLLGMCLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPV 522

  Fly   955 KWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEI 1019
            ||.:||.....|:|:|||:||||:|:||::|.|::||.....::||:.:..|:::..|....|.:
  Rat   523 KWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASPHV 587

  Fly  1020 YEMMRQAWDLNPAKRPTFAELKVKL 1044
            |::|...|...|..||.|:.|..:|
  Rat   588 YQVMNHCWKEKPEDRPPFSRLLSQL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	29/111 (26%)
		PTKc_Csk_like	793..1047	CDD:270635	106/259 (41%)
		STYKc	800..1044	CDD:214568	101/250 (40%)
Itk	NP_001102295.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810