Protein Alignment Csk and Ror

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_476962.1
• Gene: Ror / 34367
• FlyBaseID: FBgn0010407
• Length: 685
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 132/468 - (28%)
• Similarity: 210/468 - (44%)
• Gaps: 79/468 - (16%)

  Fly   635 GVTAGSGVNASSAWSSGST------------------TAMNHASLSPTALAPQQGRSRCEVKLNA 681
            |:|.......:..|..|||                  ..|...|..|..:.....|:...|:.:
  Fly   226 GITIEVDKTENCYWEDGSTYRGVANVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENS- 289

  Fly   682 MPWFHGSITRDEAEHLLQ-PR-EDGLFLVRESTN------FPGDYTLCVCFQSKVEHYRVKYLEN 738
             ||.....:|:....|.. |: .|.:::....|.      |...:.:.:..:..:.||.::.:.|
  Fly   290 -PWCFVDSSRERIIELCDIPKCADKIWIAIVGTTAAIILIFIIIFAIILFKRRTIMHYGMRNIHN 353

  Fly   739 KLT--IDDEEYFE------------NLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFV 789
            ..|  .|...|..            |||.|..|.     .|.::||:....|....|.:...:|:
  Fly   354 INTPSADKNIYGNSQLNNAQDAGRGNLGNLSDHV-----ALNSKLIERNTLLRINHFTLQDVEFL 413

  Fly   790 DKGWVIPEAELQLRESIGKGEFGDVMLG-ILRNEK----VAVKMLKDEGAV---QKFLAEASVMT 846
                          |.:|:|.||.|..| :|:..|    ||:|.||:..:|   |.|..|..:::
  Fly   414 --------------EELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELIS 464

  Fly   847 TLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIF---AYDTASGMEY 908
            .|:|.|:|..:|:|...:...::.|||:.|.|.::|.|..........|:.|   |...:.||:|
  Fly   465 DLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQY 529

  Fly   909 LEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGK------LPIKWTAPEALKNGRF 967
            |.|...|||||||||.|::|..|.|:|||||:| :.|:.|..:      ||::|...|::..|:|
  Fly   530 LSAHHYVHRDLAARNCLVNEGLVVKISDFGLSR-DIYSSDYYRVQSKSLLPVRWMPSESILYGKF 593

  Fly   968 SNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPA 1032
            :.:||:||||::||||||:|..||......:|:..:.....:.|||.||..:|.:|.:.|.....
  Fly   594 TTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSV 658

  Fly  1033 KRPTFAELKVKLQ 1045
            |||||.::..:|:
  Fly   659 KRPTFTDISNRLK 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	22/118 (19%)
		PTKc_Csk_like	793..1047	CDD:270635	96/270 (36%)
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	1/1 (100%)
		KR	235..312	CDD:214527	14/78 (18%)
		PTKc_Ror	404..673	CDD:270642	98/283 (35%)