Protein Alignment Csk and Map3k9

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_017170611.1
• Gene: Map3k9 / 338372
• MGIID: 2449952
• Length: 1120
• Species: Mus musculus
• Alignment Length: 379
• Identity: 104/379 - (27%)
• Similarity: 154/379 - (40%)
• Gaps: 80/379 - (21%)

  Fly   743 DDEEYFENLGQ--------LVAHYE-ADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGW----- 793
            |:||....||.        .|..|| |..|.|..:|...:..|.|     :|:...|:||
Mouse    33 DEEEAAAELGSHAALPYWTAVFEYEAAGEDELTLRLGDVVEVLSK-----DSQVSGDEGWWTGQL 92

  Fly   794 -----------VIPE---------------------------AELQLRESIGKGEFGDVMLGILR 820
                       |.|.                           |||.|.|.||.|.||.|......
Mouse    93 NQRVGIFPSNYVTPRSAFSSRCQPGAEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWA 157

  Fly   821 NEKVAVKMLK---DEG---AVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLV 879
            .::||||..:   ||.   .::....||.:...|:|.|::...|:.....:|.||.|:...|.|.
Mouse   158 GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLN 222

  Fly   880 DYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVV---HRDLAARNVLISE--------DCVAK 933
            ..|..:   .|.....:.:|...|.||.||..:.:|   ||||.:.|:||.:        :.:.|
Mouse   223 RVLSGK---RIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILK 284

  Fly   934 VSDFGLAREECYNLDVGKL-PIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLA 997
            ::|||||||......:... ...|.|||.::...||..||:||:|:||||:.: |.||:..|...
Mouse   285 ITDFGLAREWHRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLT-GEVPFRGIDGL 348

  Fly   998 DVVKHVEVG-YKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLNNA 1050
            .|...|.:. ..:..|..||....::|...|:.:|..||:|..:..:|..:..:
Mouse   349 AVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEES 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	12/42 (29%)
		PTKc_Csk_like	793..1047	CDD:270635	87/315 (28%)
Map3k9	XP_017170611.1	SH3_MLK1-3	49..106	CDD:212992	14/61 (23%)
		STKc_MLK1	130..399	CDD:271047	84/272 (31%)