Protein Alignment Csk and CG3277

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_608762.3
• Gene: CG3277 / 33543
• FlyBaseID: FBgn0031518
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 164/723 - (22%)
• Similarity: 263/723 - (36%)
• Gaps: 238/723 - (32%)

  Fly   462 SSHALNSHNLISSASNHS---PKSPS--------------QTQQQQQTTNQQQQQQQQQASHSIL 509
            |.:.:...|  :||..||   |.:|:              |.|...:|:|...::..:......|
  Fly   131 SEYGIKEKN--ASAETHSVNLPVNPNLNVESVDCNYMFGCQYQVIVETSNAMVRRSARVYIPQCL 193

  Fly   510 S-----TFAPAP--TVAAVQPAGSQSVAGTAAAVAA-VAQQQQQQHL---------QLLAN---- 553
            .     ..||.|  .:|..:...:::::...:.:|: :.:::|..||         ||..|
  Fly   194 EGKCSCQLAPTPPKVLAVAKMLSNETISINLSILASELLRKEQDSHLHETLRTYKMQLKINEETN 258

  Fly   554 --CPPGGA--GLMS-----SSLN--AAQMGMHGAERALPPKSLALSGSQHGSNMLLHTAPQPPQA 607
              .|.||.  .||:     |.||  |...|..|..:.    .|.....:..|..|......|...
  Fly   259 PSLPWGGVLKHLMTRVYKLSELNFRATPKGFEGVMKL----GLGTQLKEKASLSLQAVIIDPTGC 319

  Fly   608 SQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQGR 672
            ..|.:|..|....:..:           :|.|..|:.|....|....|:..|.|  ..|..::.|
  Fly   320 EGPRSVTKVPVPANPVL-----------LTEGDSVSNSIIVMSAMLIAIILAGL--IMLLLRRRR 371

  Fly   673 SRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLE 737
            :|...||           |.:.:..:|........:.::.|                 |..||:|
  Fly   372 ARTTAKL-----------RKQEQIYIQTFATSAIEMEDNVN-----------------YVDKYVE 408

  Fly   738 NKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQL 802
            ....:...:.||                                             :|.:.:|:
  Fly   409 KSQVLGLADIFE---------------------------------------------VPHSAIQI 428

  Fly   803 RESIGKGEFGDVMLGILRNEK-------VAVKMLK-----DEGAVQKFLAEASVMTTL-EHDNLV 854
            ...:|:|.||.|......|.:       ||||.||     ||  |.::|||..::..: .|.|:|
  Fly   429 GRMLGEGAFGQVHEATAINLRRMRGTTIVAVKQLKPNPKADE--VAEYLAEIEMLKGVGTHHNVV 491

  Fly   855 KFIGLVFTSKHLYLVTEYMSKGSLVDYLR-----------------------SRGRQHITKKDQI 896
            .|:|.........::.||::||:|:.|||                       :|.....:.|.|.
  Fly   492 SFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKEASKLRNRNANYTSCRPIMTRTNSTSSPKSQS 556

  Fly   897 I----------------------------------------------------------FAYDTA 903
            :                                                          ||...|
  Fly   557 VNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSFAETTYTIVEDEDAFEYILDNKELHNFALQIA 621

  Fly   904 SGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECY-NLDVGKLPIKWTAPEALKNGRF 967
            :||.:||.:::.|||||||||||..:...|:|||||:|...| |....|||::|.:.||::...:
  Fly   622 NGMRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHGIYTNTRTRKLPLRWLSIEAIRENVY 686

  Fly   968 SNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPA 1032
            |:|||:|::|::||||.:.|..|||.|...:::..:..|.::|.||.|.|::|.:|.|.|...|.
  Fly   687 SSKSDIWAYGVVLWEIGTLGASPYPTISNDELIPFLMAGNRLERPEICTPQVYTIMLQCWLEEPE 751

  Fly  1033 KRPTFAEL 1040
            :||||..|
  Fly   752 ERPTFDAL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	9/96 (9%)
		PTKc_Csk_like	793..1047	CDD:270635	100/343 (29%)
CG3277	NP_608762.3	PTKc	430..763	CDD:270623	98/332 (30%)