Protein Alignment Csk and Wsck

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Alignment Length: 691
• Identity: 149/691 - (21%)
• Similarity: 250/691 - (36%)
• Gaps: 226/691 - (32%)

  Fly   537 AAVAQQQQQQHLQL-----LAN----CPPGGAGLMS--SSLNAAQMGMH---------------- 574
            |.|.:.|:||..||     |||    |  ||.|:.|  |::...|.|.|
  Fly    87 ANVLEPQEQQDEQLCNTRCLANKAQYC--GGVGVHSYYSTILTKQPGPHHLRISNKTENSLTLSW 149

  Fly   575 ------------GAERALPPKSLALSGSQHGSNML-----LHTAPQPPQASQPAAVVGVSGSGSA 622
                        |||..||.:.|        .|.|     |.|....|...||..:|
  Fly   150 NAYEARKLLLAGGAEAVLPNQLL--------DNFLIKAQVLKTYSSLPAFPQPEFMV-------- 198

  Fly   623 GMST------------SLHSFDINGVTAGSGVNASSAWSSGSTTAMNHASL-SPTALAPQ-QGRS 673
             .||            :|::..:..:...:.|..|.. ...|..|.....| ||....|: ..|:
  Fly   199 -QSTETQFELTDLHPATLYNISVRAMCKDAQVGQSEC-GQASIEATTEVGLPSPVPAQPKILSRT 261

  Fly   674 RCEVKLNAMP----------------WFHGSITRDEAEHLL----QPREDGL------------- 705
            ...|.:...|                :...::::.....||    |.::||:
  Fly   262 DRTVTIELSPIRNDNGPLSKLLVIVEYVDNALSQPFDAQLLGSWQQAQQDGVPYYIAAELDYDRP 326

  Fly   706 -------FLVRES------TNFPGDYT---------LCVCFQ--SKVEHYRVKYLENKLTIDDEE 746
                   |:|.:.      ||.|.|..         |....:  :|..:.|..:.::..::||..
  Fly   327 EDNRTRRFVVGDGKRYGRFTNKPLDQPDAHVHISLGLVSTLEGVTKTMYSRGTHDQHVTSLDDFS 391

  Fly   747 Y--FENLGQ--------------------LVAHY---------------------------EADA 762
            |  ||. ||                    |:|::                           |.:.
  Fly   392 YATFEK-GQSSVVALAVTCVIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQTPIIEREN 455

  Fly   763 DGLCTQ--LIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQL--RESIGKGEFGDVMLG------ 817
            :|...:  .:...|:..||:.    :..|:....||...|:|  .:.||.|.||:::.|
  Fly   456 NGYLVEDDPLPHSPENFKQQL----QQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTND 516

  Fly   818 ILRNEKVAVKMLKD-EGAVQ-KFLAEASVMTTLE-HDNLVKFIGLVFTSKHLYLVTEY--MS-KG 876
            ..|:..:.|..|.| .|..| :.|.|...::.|: .::|:.|.|:..:....||:.|.  || |.
  Fly   517 FARDCTLHVLCLDDLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFEQQRMSLKR 581

  Fly   877 SLVDYLRSRGRQHITK-KDQII--FAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFG 938
            .||:.........:|. .:|::  :.|:.||.|.||.:.:||||.|.:.:|.::.|...|:|.||
  Fly   582 KLVESRLMAPSPRLTSLSEQLVLQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFG 646

  Fly   939 ------LAREE-CYNLDVGKLPIKWTAPEALKN-GRFSNKSDMWSFGILLWEIYSFGRVPYPRIP 995
                  :||:: .:|        :|.|||.|:: ...|.:||:||...:.||..:.|..||....
  Fly   647 PLPYMNIARQQPDHN--------RWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYANAV 703

  Fly   996 LAD--VVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKR 1034
            .::  :::.:....:...|.....::|:::...|.|.|::|
  Fly   704 ASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEPSER 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	27/204 (13%)
		PTKc_Csk_like	793..1047	CDD:270635	73/269 (27%)
		STYKc	800..1044	CDD:214568	71/262 (27%)
Wsck	NP_733018.1	WSC	42..115	CDD:280068	11/29 (38%)
		fn3	130..222	CDD:278470	19/108 (18%)
		TyrKc	493..746	CDD:197581	70/260 (27%)
		PTKc	497..750	CDD:270623	69/256 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24418
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010