Protein Alignment Csk and Map3k10

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001382027.1
• Gene: Map3k10 / 308463
• RGDID: 1308381
• Length: 940
• Species: Rattus norvegicus
• Alignment Length: 275
• Identity: 93/275 - (33%)
• Similarity: 134/275 - (48%)
• Gaps: 23/275 - (8%)

  Fly   795 IPEAELQLRESIGKGEFGDVMLGILRNEKVAVKMLK----DEGAV--QKFLAEASVMTTLEHDNL 853
            ||..||||.|.||.|.||.|...:.|.|:||||..:    .:.||  ::...||.:...|:|.|:
  Rat    93 IPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNI 157

  Fly   854 VKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLE---AKKVV 915
            :...|...:..:|.||.||...|:|...|..|   .:.....:.:|...|.||.||.   ...::
  Rat   158 IALRGACLSPPNLCLVMEYARGGALSRVLAGR---RVPPHVLVNWAVQVARGMNYLHNDAPVPII 219

  Fly   916 HRDLAARNVLISE--------DCVAKVSDFGLAREECYNLDVGKL-PIKWTAPEALKNGRFSNKS 971
            ||||.:.|:||.|        |.|.|::|||||||......:... ...|.|||.::...||..|
  Rat   220 HRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSS 284

  Fly   972 DMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVG-YKMEAPEGCPPEIYEMMRQAWDLNPAKRP 1035
            |:||||:||||:.: |.|||..|....|...|.:. ..:..|..||.....::.:.||.:|..||
  Rat   285 DVWSFGVLLWELLT-GEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRP 348

  Fly  1036 TFAELKVKLQLLNNA 1050
            .|..:..:|:::..:
  Rat   349 DFGSILKQLEVIEQS 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190
		PTKc_Csk_like	793..1047	CDD:270635	93/270 (34%)
Map3k10	NP_001382027.1	SH3_MLK1-3	20..76	CDD:212992
		Protein Kinases, catalytic domain	103..360	CDD:473864	86/260 (33%)
		Leucine-zipper 1	384..405
		Leucine-zipper 2	419..440
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	490..599
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	639..658
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	687..732
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	748..916