Protein Alignment Csk and Srms

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001011961.1
• Gene: Srms / 296472
• RGDID: 1306602
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 475
• Identity: 159/475 - (33%)
• Similarity: 245/475 - (51%)
• Gaps: 56/475 - (11%)

  Fly   605 PQASQPAAVVGVS-GSGSAGMSTSLHSFDIN-----GVTAGSGVNA-------------SSAWSS 650
            |...|||||...| .:..|.:..:|:.|...     .|:.|..:.|             |...|:
  Rat    50 PVPEQPAAVEPCSFPAPRARLFRALYDFTARCAEELSVSRGDRLYALKEEGEYIFAQRLSGPPST 114

  Fly   651 GSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLL--QPREDGLFLVRESTN 713
            |.......|..:|...:.|             ||:...|:|.:|:.||  .....|.||:|.|.:
  Rat   115 GLVPVTYLAKATPETPSDQ-------------PWYFNGISRTQAQQLLLSPANAPGAFLIRPSES 166

  Fly   714 FPGDYTLCVCFQSKVEHYRVKYL-ENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIK-CLPK- 775
            ..|.|:|.|..|:||.|||:... ...|.:.:...|.:|..|:|:|:.:...:...|:: |:|:
  Rat   167 SIGGYSLSVRAQAKVCHYRICMAPSGGLYLQEGRLFPSLDALLAYYKTNWKLIQNPLLQPCVPQM 231

  Fly   776 -LGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGI-LRNEKVAVKMLKD-EGAVQK 837
             |.:.|            |..|.:|..||..:|:|.||:|..|: |.:..||||::|. :..:..
  Rat   232 PLAQDE------------WERPRSEFVLRRKLGEGFFGEVWEGLWLGSTPVAVKVIKSADMKLAD 284

  Fly   838 FLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDT 902
            ...|...:.:|.|:.|::...:....:.:|:|||.|.||:|..||.|...:.::....:.||...
  Rat   285 LTKEIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYLGSPEGKALSLPHLLGFACQV 349

  Fly   903 ASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAR---EECYNLDVG-KLPIKWTAPEALK 963
            |.||.|||.::||||||||||||:.:|...||:||||||   ::.|:...| |:|:|||||||..
  Rat   350 AEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAAN 414

  Fly   964 NGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWD 1028
            ...||.|||:|||||||:|::::|:.||..:...:.::.:..||::..|..||.|:|.:|.:.|.
  Rat   415 YRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYMLMVECWK 479

  Fly  1029 LNPAKRPTFAELKVKLQLLN 1048
            .:|.:|||||.|:.||..:|
  Rat   480 GSPEERPTFATLREKLNAIN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	31/102 (30%)
		PTKc_Csk_like	793..1047	CDD:270635	106/259 (41%)
		STYKc	800..1044	CDD:214568	101/249 (41%)
Srms	NP_001011961.1	SH3	70..124	CDD:302595	8/53 (15%)
		SH2	134..212	CDD:301589	27/77 (35%)
		PTKc_Srm_Brk	238..498	CDD:133248	106/259 (41%)
		Pkinase_Tyr	245..495	CDD:285015	101/249 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0197
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820