Protein Alignment Csk and T21G5.1

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001355382.1
• Gene: T21G5.1 / 266839
• WormBaseID: WBGene00020659
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 136/458 - (29%)
• Similarity: 215/458 - (46%)
• Gaps: 83/458 - (18%)

  Fly   634 NGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQGRSRCEV---------KLNAMPWFHGSI 689
            ||:|.|..       ..||..:.|.....|   .|::......|         ::....::||.|
 Worm    30 NGITTGGS-------REGSKESANPPGTPP---PPEEKPKEPMVDVPVVQITPEIKGCQFYHGII 84

  Fly   690 TRDEAE--------HLL---QPRED--GLFLV----RESTNFPGDYTLCVCFQSK---VEHYRVK 734
            .|.:||        :||   :|||:  |.||:    ||:     .:......|.|   .:.|.:.
 Worm    85 PRVDAELSLRYVGDYLLRRAEPRENAGGQFLIISVKREA-----GFVHVPISQDKEGAKQFYFMP 144

  Fly   735 YLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAE 799
            .|:....:|          |:..:.|.|..:|.|....|           .|..:...|:||..:
 Worm   145 TLKENTVLD----------LIDVHLARAQPVCVQWNVYL-----------RKPVLRATWIIPHED 188

  Fly   800 LQLRESIGKGEFGDVMLGIL---RNEKV---AVKMLKDEGAVQ---KFLAEASVM-TTLEHDNLV 854
            :.|...||.|.||:|.|..:   .:|.|   |||.||.|..:.   :|:.||.:| ...:|.::|
 Worm   189 VILYRKIGSGAFGEVFLARMVDPTSEYVLDCAVKKLKQEATMDAKLRFMKEARMMLKNYKHKHIV 253

  Fly   855 KFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDL 919
            ...|:...:..|.::.|....|||:.||| :.:..:|..:::.|:.:.:||:.|||..:.:|||:
 Worm   254 MIFGIATLNSPLLILMELCPNGSLISYLR-KNKGKVTLLEKLRFSAEASSGLAYLEKMECIHRDI 317

  Fly   920 AARNVLISEDCVAKVSDFGLAREE----CYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILL 980
            ||||.|:|.....|:||.|||.::    .|:||  ||||||.|||.:::..:|.|||:|:|||::
 Worm   318 AARNCLLSAKNEIKISDLGLADDKGMVIDYSLD--KLPIKWLAPEIMQDKVYSLKSDIWAFGIMI 380

  Fly   981 WEIYSFGRVPYPRIPLADV-VKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKL 1044
            |||::.|..|||.:..... .|.|.:.|:|:.|:..|.|:.:::...|..:|..|.|.......|
 Worm   381 WEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTELVQVIDTCWKKDPDMRQTMVLHSSAL 445

  Fly  1045 QLL 1047
            |||
 Worm   446 QLL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	27/116 (23%)
		PTKc_Csk_like	793..1047	CDD:270635	96/268 (36%)
T21G5.1	NP_001355382.1	SH2_Fps_family	72..165	CDD:198224	24/107 (22%)
		STYKc	189..438	CDD:214568	90/251 (36%)