Protein Alignment Csk and Styk1

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_766479.1
• Gene: Styk1 / 243659
• MGIID: 2141396
• Length: 429
• Species: Mus musculus
• Alignment Length: 320
• Identity: 88/320 - (27%)
• Similarity: 140/320 - (43%)
• Gaps: 58/320 - (18%)

  Fly   759 EADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIP-EAELQLRESIGKGEFGDVMLGIL--- 819
            |...:|.   |....|:|.|.:              :| |..|::.|.|..|..|.:....:
Mouse    94 ETSVEGF---LRAATPRLAKLQ--------------VPREQLLEVLEQIHSGSCGTLYHATMTTK 141

  Fly   820 ---RNEKVAVKMLKDE---GAVQKFLAEASVMTTL-EHDNLVKFIGLVFTSKHLYLVTEYMSKGS 877
               :.:.|.:|.|:|.   ..||.|:........| :|.|||:..|.......||::.|.:..|.
Mouse   142 DHPKPKSVVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGD 206

  Fly   878 LVDYLRSRGRQ-----------------HITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVL 925
            |:.:|.:..|.                 ||.|  ||:.|      :|:|:.|.:.|.|:||||:|
Mouse   207 LLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGK--QILLA------LEFLQEKHLFHGDVAARNIL 263

  Fly   926 ISEDCVAKVSDFGLARE-----ECYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYS 985
            |..|...|:...|||.|     ...:.....:|:||.|||.|.....|.:.|:|||||||:|:.:
Mouse   264 IQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWLAPERLLLRPASIRGDIWSFGILLYEMVT 328

  Fly   986 FGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ 1045
            .|..|||.:|...::::::....|:.|..|...:|.:|:..|..:...||...:|..:|:
Mouse   329 LGAPPYPEVPPTSILQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDSRPLLGQLLQRLE 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	4/17 (24%)
		PTKc_Csk_like	793..1047	CDD:270635	82/286 (29%)
Styk1	NP_766479.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..83
		Protein Kinases, catalytic domain	123..388	CDD:473864	78/272 (29%)