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Protein Alignment Csk and Syk

DIOPT Version :10

Sequence 1:	NP_731611.2	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_035648.2	Gene:	Syk / 20963	MGIID:	99515	Length:	629	Species:	Mus musculus

Alignment Length:	462	Identity:	150/462 - (32%)
Similarity:	222/462 - (48%)	Gaps:	103/462 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   682 MPWFHGSITRDEAEH--LLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRV-KYLENKLTID 743
            ||||||:|:|||:|.  |:..:.:|.||:|...| .|.|.||:..:.||.|||: :....||:|.
Mouse   165 MPWFHGNISRDESEQTVLIGSKTNGKFLIRARDN-SGSYALCLLHEGKVLHYRIDRDKTGKLSIP 228

  Fly   744 DEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQ----------------------------- 779
            :.:.|:.|.|||.||....|||...|.....|:|.|
Mouse   229 EGKKFDTLWQLVEHYSYKPDGLLRVLTVPCQKIGAQMGHPGSPNAHPVTWSPGGIISRIKSYSFP 293

  Fly   780 ---------------EFCINSKDF--------VDKG----------------WVIPEAELQLRE- 804
                           |..::...:        .|:|                :..|| |::.:|
Mouse   294 KPGHKKPAPPQGSRPESTVSFNPYEPTGGPWGPDRGLQREALPMDTEVYESPYADPE-EIRPKEV 357

  Fly   805 ------------SIGKGEFGDVMLGILRNEK----VAVKMLKDE----GAVQKFLAEASVMTTLE 849
                        .:|.|.||.|..|..:.:|    ||||:||:|    ....:.||||:||..|:
Mouse   358 YLDRSLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD 422

  Fly   850 HDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKV 914
            :..:|:.|| :..::...||.|....|.|..||:.  .:||..|:.|...:..:.||:|||....
Mouse   423 NPYIVRMIG-ICEAESWMLVMEMAELGPLNKYLQQ--NRHIKDKNIIELVHQVSMGMKYLEESNF 484

  Fly   915 VHRDLAARNVLISEDCVAKVSDFGLAR-----EECYNLDV-GKLPIKWTAPEALKNGRFSNKSDM 973
            |||||||||||:.....||:|||||::     |..|.... ||.|:||.|||.:...:||:|||:
Mouse   485 VHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDV 549

  Fly   974 WSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFA 1038
            ||||:|:||.:|:|:.||..:..::|...:|.|.:|..|.|||.|:|::|...|..:...||.|.
Mouse   550 WSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFT 614

  Fly  1039 ELKVKLQ 1045
            .::::|:
Mouse   615 AVELRLR 621

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.