Protein Alignment Csk and Srms

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_035611.4
• Gene: Srms / 20811
• MGIID: 101865
• Length: 496
• Species: Mus musculus
• Alignment Length: 376
• Identity: 139/376 - (36%)
• Similarity: 217/376 - (57%)
• Gaps: 20/376 - (5%)

  Fly   683 PWFHGSITRDEAEHLL--QPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYL-ENKLTIDD 744
            ||:...|:|.:|:.||  .....|.||:|.|.:..|.|:|.|..|:||.|||:... ...|.:.:
Mouse   123 PWYFSGISRAQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVRAQAKVCHYRICMAPSGSLYLQE 187

  Fly   745 EEYFENLGQLVAHYEADADGLCTQLIK-CLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGK 808
            .:.|.:|..|:|:|:.:...:...|:: |:|::          ..|...|..|.:|..||..:|:
Mouse   188 GQLFPSLDALLAYYKTNWKLIQNPLLQPCIPQI----------PLVQDEWERPRSEFVLRRKLGE 242

  Fly   809 GEFGDVMLGI-LRNEKVAVKMLKD-EGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTE 871
            |.||:|..|: |.:..||||::|. :..:.....|...:.:|.|:.|::...:....:.:|:|||
Mouse   243 GFFGEVWEGLWLGSIPVAVKVIKSADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVYIVTE 307

  Fly   872 YMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSD 936
            .|.||:|..||.|...:.::....:.||...|.||.|||.::||||||||||||:.:|...||:|
Mouse   308 LMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVAD 372

  Fly   937 FGLAR---EECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLA 997
            |||||   ::.|:...| |:|:|||||||.....||.|||:|||||||:|::::|:.||..:...
Mouse   373 FGLARLLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNH 437

  Fly   998 DVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLN 1048
            :.::.:..||::..|..||.|:|.:|.:.|..:|.:|||||.|:.||..:|
Mouse   438 ETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILREKLNAIN 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	31/97 (32%)
		PTKc_Csk_like	793..1047	CDD:270635	106/259 (41%)
Srms	NP_035611.4	None