Protein Alignment Csk and ZK622.1

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_494994.1
• Gene: ZK622.1 / 191366
• WormBaseID: WBGene00022780
• Length: 419
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 124/392 - (31%)
• Similarity: 210/392 - (53%)
• Gaps: 50/392 - (12%)

  Fly   682 MPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGD---YTLCVCFQSKVEHYRVKYLENKLTID 743
            |.|:||.:.|.:...||:  .||.||||.|.....|   ..|.|.::.|..|::::..|:...:.
 Worm    30 MDWYHGLLPRADINTLLE--NDGDFLVRTSHIVGQDSAKTVLSVKWKGKCHHWQLQEKEDGSIVI 92

  Fly   744 DEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFC-------INSKDFVDKGWVIPEAELQ 801
            :|..||::          .|.:.|..:|.||....   |       ||.:|     |.:...:::
 Worm    93 EERKFESV----------LDMVTTLRMKRLPVSAN---CPALLLNPINKQD-----WELRHDQIK 139

  Fly   802 LRESIGKGEFGDVMLGIL--RNEK--VAVKM------LKDEGAVQKFLAEASVMTTLEHDNLVKF 856
            |.:.:|:|.||.|.....  :.||  ||||:      :.....::....||.:|...:|.|:|.|
 Worm   140 LGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCF 204

  Fly   857 IGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAA 921
            .|:....:.:.||.|..|:|:|..:|::. :.:::.:|::.:::|.:.|:|||.....:|||:||
 Worm   205 FGVCVEKEPIMLVMELASQGALDSFLKNE-KNNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAA 268

  Fly   922 RNVLISEDCVAKVSDFGLARE-----ECYNL-DV-GKLPIKWTAPEALKNGRFSNKSDMWSFGIL 979
            ||.|:.:: |.|::||||:::     ..|.| |: .||||:|.|||.:....::.|||::|||||
 Worm   269 RNFLMHKN-VVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGIL 332

  Fly   980 LWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYE-MMRQAWDLNPAKRPTFAELKVK 1043
            ||||:..|.:|||.:.||:|.:.|:.||:|:||:..|..:.. |:.|.|..||..|....|:::.
 Worm   333 LWEIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLA 397

  Fly  1044 LQ 1045
            ::
 Worm   398 ME 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	28/97 (29%)
		PTKc_Csk_like	793..1047	CDD:270635	92/271 (34%)
ZK622.1	NP_494994.1	SH2_Fps_family	25..114	CDD:198224	27/95 (28%)
		TyrKc	138..398	CDD:197581	91/261 (35%)