Protein Alignment Csk and Y69E1A.3

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_502040.2
• Gene: Y69E1A.3 / 190549
• WormBaseID: WBGene00013475
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 141/514 - (27%)
• Similarity: 235/514 - (45%)
• Gaps: 128/514 - (24%)

  Fly   590 SQHGSN-------MLLHTAPQPPQAS-----QPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGV 642
            |:|.|:       :.|:.||...:||     :|.|  ....||:..:|||:.|
 Worm     6 SEHESDDDLALECVRLNDAPSDIEASDKNPNEPGA--DKLESGNKNVSTSMMS------------ 56

  Fly   643 NASSAWSSGSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFL 707
            |:||..........:|.                 :.|:.   :||.:...|||.||  ..|..:|
 Worm    57 NSSSRDDPEEDYIRSHL-----------------INLHV---YHGVLFGSEAEKLL--TWDRAYL 99

  Fly   708 VRESTNFPGDYTLCVC--FQSKVEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADG-LCTQL 769
            ||.:...|..: ||:.  :::|:.||::.:.|                         || .|.:|
 Worm   100 VRRAITKPNKF-LCISVNWKNKIFHYQLDFNE-------------------------DGWCCKKL 138

  Fly   770 IKCLPKLGKQEFCINSKDFVDKGW---------------VIPEAELQLRESIGKGEFGDVMLGIL 819
            .:..|.:..:.| ::.:..:: .|               |:..:.:.|.:.:|.|.||:|..|..
 Worm   139 YEKFPTMPNRRF-LHIRQLLE-AWSQATPFLIPTPRGSNVLIHSTINLDKKLGCGAFGEVFKGQY 201

  Fly   820 RNE-------KVAVKMLKDEG---AVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMS 874
            :..       :||||.:....   .:|:|..||.:||.|:|:|:|.|.|.....:.:.:|.|.::
 Worm   202 KAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVT 266

  Fly   875 KGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGL 939
            .|.|..|.::  .|:|.|...:.||.:.||||.:|.:|.::||||||||.|:::|..||:|||||
 Worm   267 GGDLRKYFQT--TQNIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGL 329

  Fly   940 ARE---ECYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVP----YPRIPLA 997
            :.:   ...||:  |.||:|.|||:||:|.|:.|:|:||:|:.|.|:.:  |..    ||: .|.
 Worm   330 SLQGTVTTKNLE--KAPIRWLAPESLKSGLFNEKTDVWSYGVFLTELMT--RCEHDPLYPK-SLK 389

  Fly   998 DVVKHV---EVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELK-----VKLQLLN 1048
            |....:   |..:||:  .|.|.|:..::....:.||.:|..|..:|     :.::.||
 Worm   390 DAKAWILTEERPHKMK--NGDPKELMVLIDACCERNPNERLNFNTVKRQITDIYMEALN 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	23/99 (23%)
		PTKc_Csk_like	793..1047	CDD:270635	94/293 (32%)
		STYKc	800..1044	CDD:214568	92/268 (34%)
Y69E1A.3	NP_502040.2	SH2	79..162	CDD:214585	25/112 (22%)
		STYKc	182..437	CDD:214568	92/263 (35%)
		PTKc	186..438	CDD:270623	91/260 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910