Protein Alignment Csk and Y43C5B.2

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_501907.1
• Gene: Y43C5B.2 / 189849
• WormBaseID: WBGene00012785
• Length: 245
• Species: Caenorhabditis elegans
• Alignment Length: 225
• Identity: 49/225 - (21%)
• Similarity: 102/225 - (45%)
• Gaps: 59/225 - (26%)

  Fly   683 PWFHGSITRDEAEHLLQPREDGLFLVRES---TNFPGDYTLCV--C---FQSKVEHYRVKYLENK 739
            |::||.:.|::.:.:|  :.:|.|::|.|   ...|....|.|  |   .:.:::||.:|...:|
 Worm    17 PYYHGFLPREDVKTVL--KNNGDFVIRISEPQAGSPRSNILSVMHCVPPMEEEIKHYVIKTKGDK 79

  Fly   740 LTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDK-----------GW 793
            :.|:...:..                       :|::  .|:.:..|:.|.|           .|
 Worm    80 IFIEKVSFLS-----------------------IPEM--VEWHLTKKESVQKDVFLIKAISRQAW 119

  Fly   794 VIPEAELQLRESIGKGEFGDVMLGILRNEK------VAVKMLK----DEGAVQKFLAEASVMTTL 848
            .:....::..:.:|:|.||:||:|.::..|      ||:|..|    .:..:::|:.||.||.:|
 Worm   120 ELDHDNIEPLKKLGEGAFGEVMMGTMKFRKGGKSVQVAIKQAKLSNLTKEQIKEFMGEARVMRSL 184

  Fly   849 EHDNLVKFIGLVFTSKHLYL---VTEYMSK 875
            .|.::|:|.|:.....::.|   :.|:::|
 Worm   185 SHPHVVRFYGVPRRRVNVALCRSLNEFLAK 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	19/101 (19%)
		PTKc_Csk_like	793..1047	CDD:270635	26/96 (27%)
Y43C5B.2	NP_501907.1	SH2_Fps_family	11..104	CDD:198224	21/113 (19%)
		Protein Kinases, catalytic domain	129..>218	CDD:473864	25/86 (29%)