Protein Alignment Csk and T25B9.4

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_501994.1
• Gene: T25B9.4 / 188882
• WormBaseID: WBGene00012010
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 113/390 - (28%)
• Similarity: 207/390 - (53%)
• Gaps: 46/390 - (11%)

  Fly   684 WFHGSITRDEAEHLLQPREDGLFLVREST---NFPGDYTLCVCFQSK---------VEHYRVKYL 736
            ::||.:.|::..::|:.:.|.:|.|.|.|   ....|..|.:.:.::         :::|.::..
 Worm    16 FYHGYLPREDLPYVLKKKGDFIFRVTERTVGKEQKKDIVLSIAWPTESVAMIDTKDIKNYLIERS 80

  Fly   737 ENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLP----KLGKQEFCINSKDFVDKGWVIPE 797
            .|.:.:|.:..|.::..|..||..:      :|:.  |    |||: ..|:    |.   |....
 Worm    81 ANSVWLDLKISFHSIDALYNHYRKN------ELVH--PNLRIKLGR-PICL----FF---WEFKH 129

  Fly   798 AELQLRESIGKGEFGDVMLG-ILRNEKV---AVK-MLKDEGA----VQKFLAEASVMTTLEHDNL 853
            :::.|.:.:|||.:|:|..| :.|..|.   |:| |.||..|    :::.:|||.:|.:|.|.|:
 Worm   130 SQINLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLNHPNI 194

  Fly   854 VKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRD 918
            |:..|:....:.:|:|.|:::.|.|..||: :..|.:|...:...|...|.|:|::.:..::|||
 Worm   195 VRCRGIAVLEQPVYIVIEFINGGGLDSYLK-KNSQTLTMDQKNRMAISAAWGIEFMHSHDIIHRD 258

  Fly   919 LAARNVLISEDCVAKVSDFGLARE-ECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLW 981
            :||||.|.....:.|:|||||:|: ..|.:... |:|.||.|||:|....||..||:::||:||:
 Worm   259 IAARNCLYDNKNLVKLSDFGLSRKGSVYRMKKAMKMPTKWLAPESLTTFTFSGASDVYTFGVLLY 323

  Fly   982 EIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQA-WDLNPAKRPTFAELKVKLQ 1045
            |||:. :.||..:...:..:::..|......:..|||:.|::::: :.|:||||.|...:..||:
 Worm   324 EIYTC-QEPYLAVKAGEAKRYILSGAFPNFTKQAPPELNEIVKKSIYQLDPAKRDTMKVIVKKLE 387

  Fly  1046  1045
             Worm   388  387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	21/108 (19%)
		PTKc_Csk_like	793..1047	CDD:270635	88/265 (33%)
T25B9.4	NP_501994.1	SH2_Fps_family	9..109	CDD:198224	19/98 (19%)
		PTKc	136..387	CDD:270623	85/252 (34%)