Protein Alignment Csk and Y116A8C.24

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001255917.1
• Gene: Y116A8C.24 / 178481
• WormBaseID: WBGene00013801
• Length: 528
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 125/453 - (27%)
• Similarity: 203/453 - (44%)
• Gaps: 64/453 - (14%)

  Fly   643 NASSAWSSGSTTAMNHASLSPTALAPQQGRSRC--------EVK-LNAMPWFHGSITRDEAEHLL 698
            :|.|..|..|..|.....|: |.|...:.:||.        |:: |..:.::||.:.||..|..|
 Worm    21 DAQSNRSRDSKVAPKSEGLA-TGLDETEWKSRLTTPEIVLKEIRTLEGVSYYHGMVARDLVESKL 84

  Fly   699 QPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTI--DDEEYFENLGQL-VAHYEA 760
              ...|.:|:|.:.|...::...:.|.:|      |.:.:.|||  |.|.....||.| |..:.:
 Worm    85 --TRCGDYLIRATDNRIMEFEFILSFFNK------KRIHSHLTIKCDVEAGKWALGLLSVNQFSS 141

  Fly   761 DADGLCTQLIKCLPKLGKQEFCINSKDFVDKG-WVIPEAELQLR---ESIGKGEFGDVMLG--IL 819
            ..|  .|...|..| :|...|.   |..:.|| ::|....::..   :.:|.|.|.||..|  .|
 Worm   142 VVD--LTNFYKTNP-IGAGFFL---KRAISKGKYMIAHDRIKYSPKDDLLGTGNFSDVFRGKIEL 200

  Fly   820 RNEKVAV---------------KMLKDEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLV 869
            .|:.|.|               |.:|.....::.:.||.||:.|.|.|:..|.|:......:.|:
 Worm   201 ENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQLRHANVTSFFGIAVDRLPILLI 265

  Fly   870 TEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKV 934
            .|:.:.|:|..:|...| ..|...::.::.:|.::|:.|:.|..:.|||:||||.|||.:...|:
 Worm   266 IEFCNGGNLQGHLIKFG-DRIGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVKL 329

  Fly   935 SDFGLA----REECYNL----DVG------KLPIKWTAPEALKN-GRFSNKSDMWSFGILLWEIY 984
            ||||:.    |.|....    |.|      |||::|.:||.:.. ..||..|||||.|||.:||:
 Worm   330 SDFGMGLKVRRNESAKKVAEDDDGKENKEPKLPVRWMSPELVDTPDAFSKMSDMWSLGILAYEIF 394

  Fly   985 SFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL 1047
            :....|:..:...||::.|:.|.....|....|::..:::......|.:|.|..:...:|.:|
 Worm   395 TNATKPFFNLDDTDVMQTVKSGKHPPLPLSMGPDLIRLLKDVLVAAPTQRTTADKFYNELHVL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	26/99 (26%)
		PTKc_Csk_like	793..1047	CDD:270635	81/288 (28%)
		STYKc	800..1044	CDD:214568	79/278 (28%)
Y116A8C.24	NP_001255917.1	SH2	70..155	CDD:214585	26/95 (27%)
		TyrKc	181..446	CDD:197581	78/265 (29%)
		PTKc	183..454	CDD:270623	79/271 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910