Protein Alignment Csk and kin-26

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_501309.1
• Gene: kin-26 / 177575
• WormBaseID: WBGene00002208
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 406
• Identity: 122/406 - (30%)
• Similarity: 208/406 - (51%)
• Gaps: 43/406 - (10%)

  Fly   661 LSPTALAPQQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGD---YTLCV 722
            :|..:|..:...:..:.:|    ::||.:..::...||.  .:|.||:|.|...||.   :.|.|
 Worm     1 MSQNSLPSEVSNATIDKEL----YYHGLLPSEDVRQLLS--NNGDFLLRSSEPEPGSPRTHILSV 59

  Fly   723 CFQSK------VEHYRVKYLENKLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEF 781
            .|.::      ::|:.|.:::.|..|:|:..|.::.:::..|:.:.    |::         :|.
 Worm    60 MFNNRLDDINSIKHFVVNFVDGKYFINDKMSFPSIQKMLGTYQRNN----TEI---------KEG 111

  Fly   782 CINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNEK------VAVKMLK----DEGAVQ 836
            |:.......:.|.:...::.:.:.:|:|.||:|..|:::.:|      ||:|.:|    .:..::
 Worm   112 CMLVNPIRRQFWELEHDQITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKAKIK 176

  Fly   837 KFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYD 901
            .|||||..|..|.|.|::||.|:....:.||||.|....|:|..:|:......:.||.::|.  .
 Worm   177 DFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVNGALDSFLKKNEDLSVDKKTEMIL--Q 239

  Fly   902 TASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLARE-ECYNLDVG-KLPIKWTAPEALKN 964
            .|.|:||:..|.::|||:||||.|.::..| |:|||||.|. ..|.:... |.||:|.|.|.:|.
 Worm   240 AAWGLEYIHGKPMLHRDIAARNCLYTDGKV-KISDFGLTRNGTVYQIKPNTKSPIRWLAIETIKT 303

  Fly   965 GRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDL 1029
            ...|.|:|:|::|:|.|||::....|||.:..|||...|..||:|........||..||.:....
 Worm   304 MICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAE 368

  Fly  1030 NPAKRPTFAELKVKLQ 1045
            ||..||:.||:...||
 Worm   369 NPNDRPSMAEIAEILQ 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	22/105 (21%)
		PTKc_Csk_like	793..1047	CDD:270635	95/265 (36%)
kin-26	NP_501309.1	SH2_Fps_family	15..108	CDD:198224	23/102 (23%)
		TyrKc	130..383	CDD:197581	92/255 (36%)