Protein Alignment Csk and C55C3.4

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_500846.1
• Gene: C55C3.4 / 177346
• WormBaseID: WBGene00016954
• Length: 431
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 123/427 - (28%)
• Similarity: 209/427 - (48%)
• Gaps: 79/427 - (18%)

  Fly   684 WFHGSITRDEAEHLLQPREDGLFLVRESTNFPGD---YTLCVCFQ--SKVEHYRVKYLENKLTID 743
            ::||.:.|::.:.:|  .:.|.||:|.|....|:   :.|.|..:  :...|:.|:..::|:.:
 Worm    11 YYHGLLPREDIQEML--NKPGQFLLRTSEPVKGEKRQFVLSVVGEKNTSANHFVVREADHKVYV- 72

  Fly   744 DEEYFENLGQLVAHYEADADGLCTQ--LIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESI 806
            |:..|..:.:||.||.:..:...|:  .:|.:.|...:.          :.|.:...:::|.:.:
 Worm    73 DKIGFPTIIELVNHYVSTKESFSTKDGTVKVVLKHAVER----------QKWELYHEDVELTKKL 127

  Fly   807 GKGEFGDVMLGIL-----RNEK---VAVKMLKDEG----AVQKFLAEASVMTTLEHDNLVKFIGL 859
            |:|.||:|..|.|     .|.:   ||||..|.|.    .:::.:.||.:|..|:|.|:|||.|:
 Worm   128 GEGAFGEVWKGKLLKILDANHQPVLVAVKTAKLESMTKEQIKEIMREARLMRNLDHINVVKFFGV 192

  Fly   860 VFTSKHLYLVTEYMSKGSLVDYLRSRGRQH--ITKKDQIIFAYDTASGMEYLEAKKVVHRDLAAR 922
            ...::.||::.|....|:|...|   |:.|  :.||.::|  |..|:|:.|:..|.::|||:|||
 Worm   193 AAGTEPLYVIMELADGGALDSAL---GKLHFPMIKKYELI--YQAANGLAYIHEKNLMHRDVAAR 252

  Fly   923 NVLISEDCVAKVSDFGLAREEC-YNLDV-GKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYS 985
            |.|.....| |::||||:||.. |.:|: .|:||:|..||.:::|.::.|:|:::||::.|||..
 Worm   253 NCLYGGGQV-KIADFGLSREGADYTMDLKKKVPIRWLPPETIRSGLYTPKTDVFAFGVMAWEITE 316

  Fly   986 FGRVPYPRIPLADVVKHVEVGYKME-APE-----------GCPPEIYE---------------MM 1023
            .|:.|||...:.:|...|..||:|. :||           .|.||.||               :.
 Worm   317 DGKEPYPGFKVIEVAMKVLQGYRMPFSPEVNKEFAEFILTKCWPEKYEDRLPMKDICKWMKSSVK 381

  Fly  1024 RQAWDLNPA----------KRPTFAELKVKLQLLNNA 1050
            .|..|..|.          ||....|.|.|...:..|
 Worm   382 AQGGDTGPGGMMSKFGKKIKRSNSRESKSKSSTMTAA 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	24/99 (24%)
		PTKc_Csk_like	793..1047	CDD:270635	98/306 (32%)
C55C3.4	NP_500846.1	SH2_Fps_family	4..93	CDD:198224	21/84 (25%)
		TyrKc	121..376	CDD:197581	89/260 (34%)