Protein Alignment Csk and W04G5.10

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_492969.2
• Gene: W04G5.10 / 173049
• WormBaseID: WBGene00012270
• Length: 412
• Species: Caenorhabditis elegans
• Alignment Length: 366
• Identity: 114/366 - (31%)
• Similarity: 170/366 - (46%)
• Gaps: 89/366 - (24%)

  Fly   736 LENKLTID-------DEEYFENLGQLVA--HYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDK 791
            :.||..:|       .|...|.:..|:.  |.|.|.:.|         |:..:.:
 Worm    60 ISNKYDLDRTRIQTESELISETIKSLIGDNHLEIDPENL---------KISTENY---------- 105

  Fly   792 GWVIPEAELQLRESIGKGEFGDVMLGILRNEK-------VAVKMLKDEGAV--QKFL-AEASVMT 846
                          ||.|.||.|....||.|:       ||||...:...:  :|.| .|.:||.
 Worm   106 --------------IGSGFFGTVYRAELRRERRNSNFMIVAVKEPSNIHNIRQKKILHEELNVMC 156

  Fly   847 TLE-HDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLR---------SRGRQHITKKDQIIFAYD 901
            ::| |.|::..:|:| |.:::.:||||:..|.|:.:||         ....:.:.|.|...|.:.
 Worm   157 SMEKHPNILSLVGVV-TQRNVMIVTEYVEDGDLLKFLRKCKFDKDSVKLDEKSLCKADLFSFTFQ 220

  Fly   902 TASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAR----EECYNLDV--GKLPIKWTAPE 960
            .|:||:|||....||||||.|||||..:.|.|::||||||    ::.|....  ..|||||.|||
 Worm   221 IANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLARRHDKKDYYRTKTTDTALPIKWLAPE 285

  Fly   961 ALKNG----RFSNKSDMWSFGILLWEIYSFGRVPYPRIP---------LADVVKHVEVGYKMEAP 1012
            ..:..    ||.:|||:||:|:.|:||:|.|..||..:.         |||.::.   |..:..|
 Worm   286 CFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLADFLRK---GNTLSEP 347

  Fly  1013 EGCPPEIYEMMRQAWDLNPAKRPTFAEL----KVKLQLLNN 1049
            |.|.|::|..|:..|:|.|.:||:|...    :.:|..|:|
 Worm   348 EHCAPKMYYFMKSCWNLIPEERPSFTACTNFSRTQLNQLSN 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	11/49 (22%)
		PTKc_Csk_like	793..1047	CDD:270635	101/296 (34%)
W04G5.10	NP_492969.2	PTKc	104..378	CDD:270623	100/301 (33%)