Protein Alignment Csk and C35E7.10

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_492826.1
• Gene: C35E7.10 / 172988
• WormBaseID: WBGene00016462
• Length: 430
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 115/373 - (30%)
• Similarity: 198/373 - (53%)
• Gaps: 54/373 - (14%)

  Fly   684 WFHGSITRDEAEHLLQPREDGLFLVRESTNFPGD---YTLCVCFQSK--VEHYRVKYLENKLTID 743
            ::||.:.|::.:.:|  .:.|.||:|.|....|:   :.|.|..:.|  ..|:.|:..::|:.:
 Worm    11 YYHGLLPREDIQEML--NKPGQFLLRTSEPVKGEKRQFVLSVVGEKKTSANHFVVRESDHKVYV- 72

  Fly   744 DEEYFENLGQLVAHYEADADGLCTQ--LIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESI 806
            |:..|..:.:||.||.:..:...|:  .:|.:.|...:.          :.|.:...:::|.:.:
 Worm    73 DKIGFPTIIELVNHYVSTKESFSTKDGTVKAVLKQAVER----------QKWELYHEDVELTKKL 127

  Fly   807 GKGEFGDVMLGIL-----RNEK---VAVKMLKDEG----AVQKFLAEASVMTTLEHDNLVKFIGL 859
            |:|.||:|..|.|     .|.:   ||||..|.|.    .:::.:.||.:|..|:|.|:|||.|:
 Worm   128 GEGAFGEVWKGKLLKILDANHQPVLVAVKTAKLESMTKEQIKEIMREARLMRNLDHINVVKFFGV 192

  Fly   860 VFTSKHLYLVTEYMSKGSLVDYLRSRGRQH--ITKKDQIIFAYDTASGMEYLEAKKVVHRDLAAR 922
            ...::.||::.|....|:|...|   |:.|  :.||.::|  |..|:|:.|:..|.::|||:|||
 Worm   193 AAGTEPLYVIMELADGGALDSAL---GKLHFPMIKKYELI--YQAANGLAYIHEKNLMHRDVAAR 252

  Fly   923 NVLISEDCVAKVSDFGLAREEC-YNLDV-GKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYS 985
            |.|.....| |::||||:||.. |.:|: .|:||:|..||.:::|.::.|:|:::||::.|||..
 Worm   253 NCLYGGGQV-KIADFGLSREGADYTMDLKKKVPIRWLPPETIRSGLYTPKTDVFAFGVMAWEITE 316

  Fly   986 FGRVPYPRIPLADVVKHVEVGYKME-APE-----------GCPPEIYE 1021
            .|:.|||...:.:|...|..||:|. :||           .|.||.||
 Worm   317 DGKEPYPGFKVIEVAMKVLQGYRMPFSPEVNKEFAEFILTKCWPEKYE 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	25/99 (25%)
		PTKc_Csk_like	793..1047	CDD:270635	90/257 (35%)
C35E7.10	NP_492826.1	SH2_Fps_family	4..93	CDD:198224	22/84 (26%)
		TyrKc	121..376	CDD:197581	89/250 (36%)