back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Csk and Fgr

DIOPT Version :9

Sequence 1:	NP_001262476.1	Gene:	Csk / 41398	FlyBaseID:	FBgn0262081	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_034338.3	Gene:	Fgr / 14191	MGIID:	95527	Length:	517	Species:	Mus musculus

Alignment Length:	499	Identity:	173/499 - (34%)
Similarity:	251/499 - (50%)	Gaps:	38/499 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   571 MGMHGAERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMSTSLHSFDI-- 633
            :|:.|..|:...:.........|....:...|..|.......:..:||:| ..:..:|:.::.
Mouse    17 VGLEGDFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTG-VTIFVALYDYEART 80

  Fly   634 -NGVTAGSGV------NASSAWSSGSTTAMNHASLSPT-ALAPQQGRSRCEVKLNAMPWFHGSIT 690
             :.:|...|.      |....|....:.:..|....|: .:||..       .:.|..|:.|.|:
Mouse    81 GDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVD-------SIQAEEWYFGKIS 138

  Fly   691 RDEAEH--LLQPREDGLFLVRESTNFPGDYTLCV--CFQSK---VEHYRVKYLE-NKLTIDDEEY 747
            |.:||.  |......|.||:|||....|.|:|.:  ..|::   ::||:::.|: ....|.....
Mouse   139 RKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQ 203

  Fly   748 FENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFG 812
            |:::..||.||....||||..|.........|...: :||    .|.|....:.|...:|.|.||
Mouse   204 FDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGL-AKD----AWEIDRNSIALERRLGTGCFG 263

  Fly   813 DVMLGILR-NEKVAVKMLKDEGAVQK-FLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSK 875
            ||.||... :.|||||.||......| ||.||.:|..|.||.||:...:| :.:.:|:|||:|..
Mouse   264 DVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVV-SEEPIYIVTEFMCY 327

  Fly   876 GSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLA 940
            |||:|:|:.|..|::.....:..|...|.||.|:|....:||||.|.|:|:.|..:.|::|||||
Mouse   328 GSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLA 392

  Fly   941 R---EECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVK 1001
            |   :..||...| |.|||||||||...|||:.|||:|||||||.|:.:.||||||.:...:|::
Mouse   393 RLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLE 457

  Fly  1002 HVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ 1045
            .||.||.|..|.|||..:||:|.|||.|:|.:||||..|:..|:
Mouse   458 QVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLE 501

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.