Protein Alignment Csk and Src64B

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_061508350.1
• Gene: Src64B / 1277104
• VectorBaseID: AGAMI1_012487
• Length: 538
• Species: Anopheles gambiae
• Alignment Length: 542
• Identity: 191/542 - (35%)
• Similarity: 277/542 - (51%)
• Gaps: 77/542 - (14%)

  Fly   540 AQQQQQQHLQLLANCPPGGAGLMSSSLNAAQMGMHGAERALPPKSLALSGSQH--GSNMLLHTAP 602
            :::|.|:    ||...|||.....||.|:...|                |.:|  |.::.....|
Mosquito     7 SKRQDQE----LALAYPGGYKKGDSSFNSNLSG----------------GPKHNNGGSIDSRYTP 51

  Fly   603 QPPQAS------------QPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGV---------NASS 646
            .|.:..            :|.....:.|..:..:..:|::::....|..|.|         :..|
Mosquito    52 DPNRGQLIKHPKGGVDIIRPRTTPLLPGHSTRRIVVALYNYNAREETDVSFVKGDRMEVLDDTES 116

  Fly   647 AWSSGSTTAMNHASLSPTALAP----QQGRSRCEVKLNAMPWFHGSITRDEAEHLLQPRED--GL 705
            .|     ..:.|.......|.|    .:.||     :|:..||..:::|.||:.||...|:  |.
Mosquito   117 DW-----WRVVHLKTRQEGLIPWNFVAEDRS-----VNSEDWFFENVSRKEADKLLLANENPRGT 171

  Fly   706 FLVRESTNFPGDYTLCV--CFQSK---VEHYRVKYLEN-KLTIDDEEYFENLGQLVAHYEADADG 764
            ||||.|.:.|..::|.|  ..:|:   |:||::|.|:| ...|...:.|.:|..||..|..:|.|
Mosquito   172 FLVRPSEHNPNGFSLSVKDWEESRGYHVKHYKIKPLDNGGYYIATNQTFPSLPALVMAYSKNALG 236

  Fly   765 LCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRNE-KVAVKM 828
            ||..|....||...|.:.: ..:..|| |.|...|:||...:|.|.||:|..|..||. :||||.
Mosquito   237 LCHVLSSPCPKPQPQVWDL-GPELRDK-WEINRNEIQLIRKLGHGNFGEVYYGKWRNNIEVAVKT 299

  Fly   829 LKDEG--AVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHIT 891
            |: ||  :.|.||.||::|....|..||....:....:.:|:|.||||||||:|:||:...|.:.
Mosquito   300 LR-EGTMSTQAFLQEAAIMKKFRHSRLVALYAVCSKEEPIYIVQEYMSKGSLLDFLRTGDGQFLQ 363

  Fly   892 KKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAR----EECYNLDVGKL 952
            .:|.|..|...||||||||.|:::|||||||||||.|:.|||:.||||||    :|.......:.
Mosquito   364 FEDLIYIAAQVASGMEYLELKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRF 428

  Fly   953 PIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEG--C 1015
            |:|||||||:..|:||.|||:||:||||.|::::|:||||.:...:|::.:|.||:|..|..  .
Mosquito   429 PVKWTAPEAIVYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIEQIERGYRMPKPTAHHL 493

  Fly  1016 PPEIYEMMRQAWDLNPAKRPTF 1037
            |.:||.:|.:.||..|.|||||
Mosquito   494 PDDIYSLMLKCWDAIPDKRPTF 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	38/104 (37%)
		PTKc_Csk_like	793..1047	CDD:270635	121/254 (48%)
Src64B	XP_061508350.1	None