Protein Alignment Csk and LOC101733045

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_031757813.1
• Gene: LOC101733045 / 101733045
• XenbaseID: XB-GENE-29086679
• Length: 568
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 171/575 - (29%)
• Similarity: 251/575 - (43%)
• Gaps: 70/575 - (12%)

  Fly   499 QQQQQASHSILSTFAPAPTVAAVQPAGS--QSVAGTAAAVAAVAQ-QQQQQHLQLLANCPPGGAG 560
            |..:|......|.|.|       .|||:  .|:.||........| .:.:.||     ....|.|
 Frog    17 QGTEQPDRGPSSKFYP-------PPAGNLPPSLPGTRGKGQGTPQVTRYKMHL-----TGTSGQG 69

  Fly   561 LMSSSLNAAQMGMHGAERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMS 625
            ...|.......|.      :|...  |.........|:| .||.|...||:..|......|....
 Frog    70 WAPSGQGKENPGF------VPQDE--LDNPMRMEPQLIH-EPQHPSPEQPSVGVLHPKQLSRAAK 125

  Fly   626 TSLHSFDI---NGVTAGSGVNASSAWSSGSTTAMNHASLSPTALAPQQGRSRCEV---------K 678
            .|::|:..   .|:....|.......:.|....:..    .|...|.|   .|.:         .
 Frog   126 VSMYSYTARSPGGMDVQRGDRLEVIGTKGPWVLVQR----ETGRGPAQ---TCYIPKSFLADAGS 183

  Fly   679 LNAMPWFHGSITRDEAEHLL--QPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLT 741
            |.|..|:.|.|.|.:|:..|  :|...|.|||..|   ...|.|.|..:..|.|||:...:....
 Frog   184 LEAEDWYFGGIRRMDAKRFLLQEPNGSGSFLVWHS---DASYWLSVRVEQTVRHYRITQAQGAYY 245

  Fly   742 IDDEEYFENLGQLVAHYEADADGLCTQLIK-C----LPKLGKQEFCINSKDFVDKGWVIPEAELQ 801
            :.:...|..||.||.:|:..:|||||:|.| |    :|::  ...|..:   ||:..:.|.:..:
 Frog   246 LVERAAFRTLGALVLYYQQQSDGLCTRLGKPCVWLDVPRM--PSLCHTA---VDQLEISPNSIER 305

  Fly   802 LRESIGKGEFGDVMLGILR-NEKVAVKMLK-DEGAVQKFL-AEASVMTTLEHDNLVKFIGLVFTS 863
            :|: :|:|.||.|.||... ..:||:|.|: ...::||.| .||..|..|.|:.|:|...:....
 Frog   306 IRK-LGRGSFGLVWLGKWNGTTQVAIKELQVTAQSLQKSLYGEADTMWKLSHERLLKLYAVCLQV 369

  Fly   864 KHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQII-FAYDTASGMEYLEAKKVVHRDLAARNVLIS 927
            ..:::|||||.:|:|..|||...:....:..|:: ||.....||.|:|....|||||.|.|:|:|
 Frog   370 SPVFIVTEYMERGTLKRYLRDHQQNRNLELQQLMDFAAQICQGMGYMEQNLCVHRDLRAENILLS 434

  Fly   928 EDCVAKVSDFGLAR-----EECYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFG 987
            .....|:.||||||     ....:.| .::||||.|||.....|:|:|||:||||:||.||.::|
 Frog   435 AMLSCKIGDFGLARFMDSSSIAMSAD-ARIPIKWMAPEVFSEQRYSSKSDVWSFGVLLVEIVTYG 498

  Fly   988 RVPYPRIPLADVVKH-VEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELK 1041
            ::|:|.|.....|:. :..|..::.|...|..:..:|...|......|||||||:
 Frog   499 KMPFPEITNEQYVREMLREGGTLQPPRDAPDNVSYIMNMCWRRAAPTRPTFAELE 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	35/103 (34%)
		PTKc_Csk_like	793..1047	CDD:270635	94/259 (36%)
LOC101733045	XP_031757813.1	SH2	185..276	CDD:472789	32/93 (34%)
		STYKc	303..556	CDD:214568	93/253 (37%)