Protein Alignment Csk and txk

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_073795552.1
• Gene: txk / 100534735
• ZFINID: ZDB-GENE-130530-553
• Length: 509
• Species: Danio rerio
• Alignment Length: 389
• Identity: 140/389 - (35%)
• Similarity: 214/389 - (55%)
• Gaps: 32/389 - (8%)

  Fly   679 LNAMPWFHGSITRDEAEHLL-QPREDGLFLVRESTNFPGDYTLCV---CF-QSKVEHYRVKYL-E 737
            :.|..|:..:|.|.|||||| |..:||.|:||.|:. |..||:.|   |. :.:|.||::|.. |
Zfish   126 IEANDWYCKNINRAEAEHLLRQEGKDGGFVVRSSSQ-PSTYTVSVYTHCLGKGEVRHYQIKRTDE 189

  Fly   738 NKLTIDDEEYFENLGQLVAHYEADADGLCTQLI-------KCLPKLGKQEFCINSKDFVDKGWVI 795
            :|..:.:...|.::.:|:.:::.:|.||..:|.       ||.|.         :..|......|
Zfish   190 DKFYLAENHVFISIPELINYHKYNAAGLVARLRYPIGPKGKCQPA---------TAGFSSDKMEI 245

  Fly   796 PEAELQLRESIGKGEFGDVMLGILR-NEKVAVKMLKDEGAVQK--FLAEASVMTTLEHDNLVKFI 857
            ..:||...:.:|.|:||.|.||..| ..|||:|.:: |||:.:  |:.||.:||.|.|..||:..
Zfish   246 NPSELTFMKELGSGQFGVVRLGKWRAQHKVAIKTIR-EGAMNEDDFIEEAKIMTRLCHPKLVQLY 309

  Fly   858 GLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAAR 922
            |:..|.:.:.:|||:|..|.|:.:||...:. :.:...:....|...||||||..:.:|||||||
Zfish   310 GVCVTQRPICIVTEFMENGCLLHFLRQHSKT-LGRSQMLCMCQDVCEGMEYLEHNQFIHRDLAAR 373

  Fly   923 NVLISEDCVAKVSDFGLAR---EECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLWEI 983
            |.|::|..|.||.|||:.|   :..|...:| :.|:||:.||.|...:||||||:||||:|:||:
Zfish   374 NCLVNERNVVKVCDFGMTRYVLDNQYTSSMGSRFPVKWSPPEVLHFNKFSNKSDVWSFGVLMWEV 438

  Fly   984 YSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL 1047
            :|.|:.|:......:||:.|..|.::..|....|.||.:|.:.|...|..||.|:||....:|:
Zfish   439 FSEGKTPFDNRTNVEVVEEVTQGSRLYRPHLATPHIYNIMYRCWHERPHGRPAFSELLQDFRLI 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	37/109 (34%)
		PTKc_Csk_like	793..1047	CDD:270635	101/260 (39%)
txk	XP_073795552.1	None