Protein Alignment Csk and ripk2

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_002939201.2
• Gene: ripk2 / 100496958
• XenbaseID: XB-GENE-493052
• Length: 553
• Species: Xenopus tropicalis
• Alignment Length: 282
• Identity: 75/282 - (26%)
• Similarity: 127/282 - (45%)
• Gaps: 33/282 - (11%)

  Fly   795 IPEAELQLRESIGKGEFGDVMLGILRN--EKVAVKMLKDEGAV-----QKFLAEASVMTTLEHDN 852
            ||..:|...:.|.||.:|.|......:  .:||||....|..:     .|.|.||.::.......
 Frog    42 IPYQKLTDLKFINKGAYGTVHSACHSDWRVRVAVKFFPTERHLVESERNKILKEAEILHKARFSY 106

  Fly   853 LVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRG-RQHITKKDQIIFAYDTASGMEYLE--AKKV 914
            ::..:|:....:.|.:|||||:.|||...|.... |..|.........|:.|.|:.:|.  ...:
 Frog   107 ILPILGICNEPECLGIVTEYMTNGSLNQLLHENAPRVEIVWPLAFRILYEIALGVNFLHNLTPSL 171

  Fly   915 VHRDLAARNVLISEDCVAKVSDFGLAREECYNLD------------VGKLPIKWTAPEALKNGRF 967
            :|.||..:|:|:..|..||::||||::....:..            :..:|.:...|.:.:|.|.
 Frog   172 LHHDLKTQNILLDRDFHAKIADFGLSKWRMLSSSHSYSDQSTPGGTIIYMPPEEYEPSSARNRRG 236

  Fly   968 SNKSDMWSFGILLWEIYSFGRVPY--PRIPLADVVKHVEVGYKME-APEGCPPEI------YEMM 1023
            |.|.||:||.|::||:.: .:.||  ...|: .::..|..|.:.: :.|..|.||      ..:|
 Frog   237 SVKHDMYSFAIIMWEVLA-RKQPYEGATTPM-QIMFSVSKGNRPDLSEESLPSEIPHRDLFISLM 299

  Fly  1024 RQAWDLNPAKRPTFAELKVKLQ 1045
            :..|..:|..||.|.:..::|:
 Frog   300 QSGWATDPNDRPAFIKCLLELE 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190
		PTKc_Csk_like	793..1047	CDD:270635	75/282 (27%)
ripk2	XP_002939201.2	Protein Kinases, catalytic domain	49..333	CDD:473864	72/275 (26%)
		DD	468..553	CDD:472698