Protein Alignment Csk and fgr

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_002934688.1
• Gene: fgr / 100493811
• XenbaseID: XB-GENE-6073541
• Length: 519
• Species: Xenopus tropicalis
• Alignment Length: 520
• Identity: 182/520 - (35%)
• Similarity: 264/520 - (50%)
• Gaps: 78/520 - (15%)

  Fly   569 AQMGMHGAERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMS--TSLHSF 631
            :||.....|...|..|..:.|...||             ||....|||:|    |::  .:|:.:
 Frog    31 SQMPFRIQETHTPFISAGIGGVIAGS-------------SQRGMGVGVTG----GVTQFIALYDY 78

  Fly   632 DI---NGVTAGSG-----VNASSA--WSSGSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFH 686
            |.   :.:|...|     :|.|..  |.:.|.::.|...:....:||..       .:.:..|:.
 Frog    79 DARTEDDLTFKKGEKFHIINNSEGDWWEARSLSSGNTGYIPSNYVAPMN-------SIQSKDWYF 136

  Fly   687 GSITRDEAEHLL----QPREDGLFLVRESTNFPGDYTLCV-----CFQSKVEHYRVKYLEN-KLT 741
            |.|.|.:||.||    .||  |.|::|||....|.|:|.|     ......:||:::.|:| ...
 Frog   137 GKIGRKDAERLLLCEGNPR--GTFMIRESETTKGAYSLSVRDWDATRGDHAKHYKIRKLDNGGFY 199

  Fly   742 IDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCIN--------SKDFVDKGWVIPEA 798
            |.....|:.:.:||.||....||||..|..  |       |||        |||    .|.|...
 Frog   200 ITTRVQFDTVEELVEHYSEFNDGLCHLLTN--P-------CINQKPQTLGLSKD----AWEITRD 251

  Fly   799 ELQLRESIGKGEFGDVMLGILR-NEKVAVKMLKDEG-AVQKFLAEASVMTTLEHDNLVKFIGLVF 861
            .:.|.:.:|:|.||||..|... ...||||.||... :.:.||.||.:|..|.||.||:...:|
 Frog   252 SISLDKKLGQGCFGDVWKGTWNGTTNVAVKTLKPSTMSPEAFLEEAQIMKKLRHDKLVQLYAVV- 315

  Fly   862 TSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQII-FAYDTASGMEYLEAKKVVHRDLAARNVL 925
            :.:.:|:|||:|:||||:|||: .|..|:.|..|:: .:...||||.|:|....:||||.|.|:|
 Frog   316 SEEPIYIVTEFMTKGSLLDYLK-EGEGHLLKLPQLVDMSGQIASGMAYIERMNYIHRDLRAANIL 379

  Fly   926 ISEDCVAKVSDFGLAR---EECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSF 986
            :.::.:.|::||||||   :..|....| |.|||||||||...|:|:.|||:|||||::.|:.:.
 Frog   380 VGDNLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGIMVCELVTK 444

  Fly   987 GRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLNNAT 1051
            ||:|||.:...:|::.||.||:|.||..|||.::|:|.|.|..:|.:||||..|:..|:....||
 Frog   445 GRIPYPGMSNREVLEQVERGYRMPAPPACPPSLHELMLQCWRGDPEERPTFEYLQSFLEDYFTAT 509

  Fly  1052  1051
             Frog   510  509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	35/106 (33%)
		PTKc_Csk_like	793..1047	CDD:270635	113/260 (43%)
		STYKc	800..1044	CDD:214568	110/250 (44%)
fgr	XP_002934688.1	SH3	72..125	CDD:388381	9/52 (17%)
		SH2_Src_Fgr	130..230	CDD:198230	34/103 (33%)
		PTKc_Src_Fyn_like	257..504	CDD:271105	110/248 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010