Protein Alignment Csk and tec

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_031751261.1
• Gene: tec / 100491653
• XenbaseID: XB-GENE-6076361
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 152/512 - (29%)
• Similarity: 240/512 - (46%)
• Gaps: 83/512 - (16%)

  Fly   577 ERALPPKSLALSGSQHGSNMLLHTAPQPPQASQPAAVVGVSGSGSAGMSTSLHSFDINGV----- 636
            ::.|||...|           :...|.||:...|.       ....|..|.:..||.:.|
 Frog   174 KKPLPPTPDA-----------IRARPPPPRPPDPE-------PEDNGEETVIAMFDFHPVEPHDL 220

  Fly   637 --TAGSG---VNASSA--WSSGSTTAMNHASLSPTALAPQQG----RSRCEVKLNAM---PWFHG 687
              ..|..   :....|  |.:.:|..             |||    ....|.||:.:   .|:..
 Frog   221 RLVTGEEYFVLEKKDAHWWKARNTYG-------------QQGYIPSNYVTEKKLDNLYQYEWYSR 272

  Fly   688 SITRDEAEHLLQPRE-DGLFLVRES-----------TNFPGDYTLCVCFQSKVEHYRVKYLE--N 738
            ::.|.:||.||:..: :|.|:||.|           |.:.|:.:.|      :.||.:|..:  .
 Frog   273 NMNRSKAEQLLKSEDKEGGFIVRNSSQAGLYTVSLYTKYGGEGSTC------IRHYHIKETQYPK 331

  Fly   739 KLTIDDEEYFENLGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLR 803
            |..:.::..|..:.:::.:::.:|.||.|:|  ..|...|.:....:..|....|.|..:||...
 Frog   332 KYYLAEKHVFNTIPEMIEYHKHNAAGLVTRL--RYPVCSKNKSAPTTAGFSYDKWEINPSELTFM 394

  Fly   804 ESIGKGEFGDVMLGILRNE-KVAVKMLKDEGAV--QKFLAEASVMTTLEHDNLVKFIGLVFTSKH 865
            :.:|.|.||.|.||..|.: |||:|.:: |||:  :.|:.||.||..|.|..||:..|:....:.
 Frog   395 KELGSGLFGVVRLGKWRAQYKVAIKAIR-EGAMSEEDFIEEAKVMMKLTHLKLVQLYGVCTQQRP 458

  Fly   866 LYLVTEYMSKGSLVDYLRSRGRQHITKKDQII-FAYDTASGMEYLEAKKVVHRDLAARNVLISED 929
            :|:|||:|..|.|::|||.|..|.  ..|.:: ...|....|.|||....:||||||||.|:::.
 Frog   459 IYIVTEFMEHGCLLNYLRQRHGQF--SPDILLSMCQDVCEAMSYLEQNNFIHRDLAARNCLVNDA 521

  Fly   930 CVAKVSDFGLAR---EECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVP 990
            .|.||||||:.|   ::.|....| |.|:||:.||.....|||:|||:||||:|:||:::.|::|
 Frog   522 GVVKVSDFGMTRYVLDDQYTSSCGAKFPVKWSPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGKMP 586

  Fly   991 YPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL 1047
            :......:||:.|..|.::..|:.....||.:|...|...|..||.|.:|..::.|:
 Frog   587 FESYSNVEVVEMVTRGERLYRPKLATKIIYSVMVACWHEKPEGRPKFFDLMKQIGLI 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	25/113 (22%)
		PTKc_Csk_like	793..1047	CDD:270635	101/261 (39%)
tec	XP_031751261.1	PH_Btk	27..168	CDD:269944
		SH3_Tec	204..259	CDD:212838	11/67 (16%)
		SH2_Tec_Itk	262..368	CDD:198259	25/113 (22%)
		PTKc_Tec_Rlk	386..645	CDD:270685	101/261 (39%)