Protein Alignment Csk and fyn

DIOPT Version :9

• Sequence 1: NP_001262476.1
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_004914619.2
• Gene: fyn / 100488004
• XenbaseID: XB-GENE-6053489
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 178/516 - (34%)
• Similarity: 260/516 - (50%)
• Gaps: 80/516 - (15%)

  Fly   591 QHGSNMLLHTAPQ----PPQASQPAAVVGVSGSGSAGMSTSLHSFDINGVTAGSGV--------- 642
            ||..:..:.|.|.    ...|.|...|.|       |:::|.|:..:. ...|:||
 Frog    37 QHYPSFTVTTIPNYNNFHTNAGQGLTVFG-------GVNSSSHTGTLR-TRGGTGVTLFVALYDY 93

  Fly   643 -------------------NASSA--WSSGSTTAMNHASLSPTALAPQQGRSRCEVKLNAMPWFH 686
                               |:|..  |.:.|.|......:....:||..       .:.|..|:.
 Frog    94 EARTEDDLSFQKGEKFQILNSSEGDWWEARSLTTGGTGYIPSNYVAPVD-------SIQAEEWYF 151

  Fly   687 GSITRDEAEHLL----QPREDGLFLVRESTNFPGDYTLCV-----CFQSKVEHYRVKYLEN-KLT 741
            |.:.|.:||..|    .||  |.:|:|||....|.|:|.:     .....|:||:::.|:| ...
 Frog   152 GKLGRKDAERQLLSFGNPR--GTYLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYY 214

  Fly   742 IDDEEYFENLGQLVAHYEADADGLCTQLI----KCLPKLGKQEFCINSKDFVDKGWVIPEAELQL 802
            |.....||.|.|||.||...|.|||.:|:    |.:|:|  .:..:.:||.    |.||...|||
 Frog   215 ITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRL--TDLSVKTKDV----WEIPRESLQL 273

  Fly   803 RESIGKGEFGDVMLGILR-NEKVAVKMLKDEGAV--QKFLAEASVMTTLEHDNLVKFIGLVFTSK 864
            .:.:|.|:||:|.:|... |.|||:|.|| .|.:  :.||.||.:|..|:||.||:...:| :.:
 Frog   274 IKRLGNGQFGEVWMGTWNGNTKVAIKTLK-PGTMSPESFLEEAQIMKKLKHDKLVQLYAVV-SEE 336

  Fly   865 HLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAARNVLISED 929
            .:|:||||||||||:|:|:....:.:...:.:..|...|:||.|:|....:||||.:.|:|:...
 Frog   337 PIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNG 401

  Fly   930 CVAKVSDFGLAR---EECYNLDVG-KLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRVP 990
            .:.|::||||||   :..|....| |.|||||||||...|||:.|||:|||||||.|:.:.||||
 Frog   402 LICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVP 466

  Fly   991 YPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLLNNAT 1051
            ||.:...:|::.||.||:|..|:.||..::|:|...|..:|.:||||..|:..|:....||
 Frog   467 YPGMNNREVLEQVERGYRMPCPQDCPNSLHELMLNCWKKDPEERPTFEYLQGFLEDYFTAT 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_001262476.1	SH2_csk_like	680..777	CDD:198190	38/110 (35%)
		PTKc_Csk_like	793..1047	CDD:270635	114/260 (44%)
		STYKc	800..1044	CDD:214568	110/250 (44%)
fyn	XP_004914619.2	SH3_Fyn_Yrk	85..140	CDD:212939	5/54 (9%)
		SH2_Src_Fyn_isoform_a_like	145..245	CDD:198281	36/101 (36%)
		PTKc_Fyn	261..534	CDD:270655	118/273 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248674at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010