Protein Alignment Csk and si:ch73-340m8.2

DIOPT Version :10

• Sequence 1: NP_731611.2
• Gene: Csk / 41398
• FlyBaseID: FBgn0262081
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_002665190.3
• Gene: si:ch73-340m8.2 / 100332982
• ZFINID: ZDB-GENE-110411-209
• Length: 480
• Species: Danio rerio
• Alignment Length: 391
• Identity: 139/391 - (35%)
• Similarity: 209/391 - (53%)
• Gaps: 39/391 - (9%)

  Fly   679 LNAMPWFHGSI-TRDEAEH-LLQP-REDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKL 740
            :.|.||:..:: ||.||:. ||:| .::|.|||.:... ...|.|.|.......|||:|..||
Zfish    98 VEAEPWYFENVKTRVEAKRCLLRPENKEGAFLVWKCDE-NNHYYLSVKNGPHARHYRIKQGEN-- 159

  Fly   741 TIDDEEY-------FENLGQLVAHYEADADGLCTQLIKCLPKLGK---QEFCINSKDFVDKGWVI 795
               |:::       |::|.:|:..|.....|||.:|.:...||.:   |....:||..:|:
Zfish   160 ---DQQFFLVHHTTFQSLRKLIEFYSKHEGGLCAKLHEACVKLDQPVPQTLSFDSKCEIDR---- 217

  Fly   796 PEAELQLRESIGKGEFGDVMLGILRN-EKVAVKMLK--DEGAVQKFLAEASVMTTLEHDNLVKFI 857
              :.|..::.:|.|||.||..|:..| .:||:|..|  :...:|   .|..:|..|.|:.|:|..
Zfish   218 --SSLTKQQKLGSGEFADVWQGLWNNTTEVAIKEFKGVNYSDIQ---TEIEIMKDLHHERLLKLY 277

  Fly   858 GLVFTSKHLYLVTEYMSKGSLVDY-LRSRGRQHITKKDQIIFAYDTASGMEYLEAKKVVHRDLAA 921
            .:..||:.:.:|||.|..|||..: ||.:.:|.:.....:.||.....||.|:| .|:|||||.|
Zfish   278 AVCTTSQPMCIVTELMKNGSLKTFLLRHKEKQDLEFSLMLDFAIQITEGMIYIE-NKIVHRDLRA 341

  Fly   922 RNVLISEDCVAKVSDFGLAR-----EECYNLDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLW 981
            .|:|::|....|::|||||:     .:..:.|| :||:||.|||...||.:::|||:|||||||.
Zfish   342 ENILLTEMQSCKIADFGLAQVNRPGNQRISSDV-RLPVKWMAPEIFDNGEYTSKSDVWSFGILLT 405

  Fly   982 EIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQL 1046
            ||.::|..|||.......|:.::.|.:|..|.|||..:|.:|...|..||.:||||.||:..|..
Zfish   406 EIVTYGDDPYPGQDKMSCVRGIQRGERMPRPAGCPESLYGIMLLCWKANPKERPTFTELREMLMA 470

  Fly  1047 L 1047
            |
Zfish   471 L 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Csk	NP_731611.2	SH2_csk_like	680..777	CDD:198190	33/106 (31%)
		PTKc_Csk_like	793..1047	CDD:270635	100/262 (38%)
si:ch73-340m8.2	XP_002665190.3	SH2	99..192	CDD:472789	31/98 (32%)
		Protein Kinases, catalytic domain	225..468	CDD:473864	98/247 (40%)