Protein Alignment CG14712 and nup124

DIOPT Version :9

• Sequence 1: NP_650096.1
• Gene: CG14712 / 41397
• FlyBaseID: FBgn0037924
• Length: 1266
• Species: Drosophila melanogaster
• Sequence 2: NP_593213.1
• Gene: nup124 / 2542254
• PomBaseID: SPAC30D11.04c
• Length: 1159
• Species: Schizosaccharomyces pombe
• Alignment Length: 1433
• Identity: 343/1433 - (23%)
• Similarity: 496/1433 - (34%)
• Gaps: 496/1433 - (34%)

  Fly    11 MSPMADSTRIDASLL---------NNRP-------AASN----FLRGLSPKGSNTSLNGTRTPER 55
            |.|::.:||..:..:         ::||       |.|:    |..||..|.|     ||.:.:|
pombe     1 MPPVSKNTRTSSKTVKKPYDPPQGSSRPFFTVLKRAFSSVLHPFTSGLDEKAS-----GTASKDR 60

  Fly    56 SLMNRSATSSSTITRQKLNLSQVDPRTFADVHSSGLSSRIVALSERS------GLQRSMSASNLY 114
            . ..|:.|.|       |...::.|      |..|.|.||:.:|.||      |::..:. :|.:
pombe    61 K-SGRAGTKS-------LLTPELTP------HYLGKSPRIIRVSNRSHVRTIDGIEEKVH-TNTF 110

  Fly   115 NPLTQPRRAPASPLPYKSRAPTL----------------------------SITQIAPPERSFYS 151
            .|     |.|.....| :.:|||                            |..|||.|:    |
pombe   111 EP-----RKPKQKQDY-TNSPTLFKRHDELSLKSLNSLHPSSALSKKLGSTSQHQIATPK----S 165

  Fly   152 GNTLSSLLRS------NSLVGLVPKTTEQEQLSRENRPILHPPHPQHESEPTRSVLEELKEISRK 210
            ..:|.::|||      |:   |...:.:|::::..| |......|.....|   :|.:.|.::|.
pombe   166 SASLLNILRSLHDEQKNT---LNISSVKQDRITEAN-PTCEKRKPSRSPSP---MLSKKKSVARA 223

  Fly   211 RINTEDTQQAQDYTKRSCQQNVDFVDFVAHHRQQQKLRNLQQQQN-------------QSFKRQR 262
            ..|           :.|.:||..|....:|    :.|.:::.::|             :|.:|:|
pombe   224 SEN-----------EPSAKQNKSFSGNDSH----KSLTDIRDKENGETEVSAKNHVPHRSSRRRR 273

  Fly   263 ELTVSVPLRHHS-TSLSAASPALQHMNSNGTISPTQSPEQVAKRPNCSY--SNDITSSLSSSCRH 324
            .....:|:.:.: ..:....|.|    .|..:....:|      .|..:  ..||...||:..
pombe   274 RHQRLIPIIYETLEQMDLRKPVL----VNAEVQTDSNP------GNTMFIDKQDIYHRLSTPT-- 326

  Fly   325 SNKRKLL-------------DMRERFQHSKNDTLASGGSSPENSPENVAKIQRKVDAEAVSKAMS 376
            |.||:.|             |:.|.|. .::|...:  :.|:.:|:: .:|...:.|........
pombe   327 SRKRQTLEKGHIKAFSAVDEDLDEIFA-CEDDVHYT--ALPKQNPKS-ERILEPIIASPKDNTSD 387

  Fly   377 MPVVTVAAVPASRAISAPAIQKAVPQVTEKP--------KLTLFNARQSQTIAEQPRPDLSSPEV 433
            ..::|.         |||..::....:|.||        .|||.||..::|...||    .|.:.
pombe   388 KGLLTK---------SAPTFEELQASITPKPVKTSPNDTALTLANAEDNKTFEHQP----LSKDT 439

  Fly   434 DAGEYAGIQFVKPKQQNSMLAAKNPSVERTHKTKLAIMLSGLKGELYLGEPDELDAPAPKSAPAP 498
            :|          ||.|.|    .:|:.|.|.:                  ..|::.|:|......
pombe   440 EA----------PKSQFS----SSPTKESTTR------------------KSEVEPPSPSKEIKS 472

  Fly   499 VTLPTPVKPIIIAPVTTSTTTVTSTATISTSAPSKPIILSNQVIKP---ADVPNTNSTGSVPKLV 560
            .....|  .....|.|.:||             .|.:.:.....||   ||| .||      :|.
pombe   473 SHFSVP--EFKFEPKTEATT-------------DKKLNVPKFEFKPTATADV-QTN------RLK 515

  Fly   561 LGQPAP------PAKTEQTPPKPIDKVPAAQADIPPKFELSTK----PVTPATSSQPLISFG--T 613
            ..:|.|      |:||::||....:| |:..:.:.||.|.:.|    |..||::|.  .|||  .
pombe   516 ENEPKPTFFAQLPSKTQETPSITENK-PSFFSQLSPKREETEKKDNAPSAPASTSG--FSFGGFA 577

  Fly   614 PKS------TAAPSFSF-----GSATNTTSSTI------------ANITN--------------- 640
            ||:      |.||:|:|     .|..:||..|:            :||.|
pombe   578 PKTLEEKEETKAPTFNFSLNNASSTQDTTKPTLQFNFGSSFGKPTSNIFNDKKTSENGLASSTVA 642

  Fly   641 ------TTTSKPIFSFGQTPANGPTVGGLSGFKTEAPATTSVS-------TTNPGTQVTSTTTFG 692
                  ...|||...||.|..:.|....|:....|.|.|.|.|       ..|......::|.|.
pombe   643 SESKPSAPESKPSSGFGNTAGSSPFSFNLTKESKEVPPTNSFSFAKKGKDEANDSLSAKASTPFS 707

  Fly   693 VTPPKT--TTTVAPTTTVSLNFGQPMPSFGAADTGVKPMFSFG----KSNNLSSGTPTTNGSDAA 751
            ...|.|  .||.||  ..|.||.:|...   |.|.:.|..:|.    |........|.| |..|:
pombe   708 FAKPNTENVTTTAP--QFSFNFTKPNTD---AKTNLLPEKTFNEEAVKQKETEKEVPPT-GPKAS 766

  Fly   752 AAKPAVFSFGGSTTQPAAAAPTPVFGSLSKPLGEGFASPGANKSETTKPSIFGNLDNGL----GN 812
            ..|.:|.|..        |.|:..|         .|.||.|..||.|..:   |:.|..    ||
pombe   767 EIKDSVSSNN--------AVPSSTF---------NFVSPFAAVSEKTNEN---NIPNDTTKTNGN 811

  Fly   813 AMKSSTNVAATTAAELPKPFGFAATTTAAGGGSTATNLFSFGGTATSKAAEPAPASQKNLFGLNA 877
            |.|.:..   .|....|..|.|.:||..|...::.:|          :..:|...:.....|:
pombe   812 ATKRTLE---QTEDAKPFAFSFGSTTEQANKKASTSN----------ETTKPQLDTSSKTDGV-- 861

  Fly   878 TTTTPFAFGGAAAGAADKSENKDNKPIAFAFGAGNNSAVANPSGVFSFGGTDKSAPPAFGSGTTS 942
            |...||:|..|.......:...|.|..|        |.:..||..||||  :.|...|..:...|
pombe   862 TANAPFSFASAFNAPKPSTNTADGKDSA--------SNLTTPSPAFSFG--NNSGVKASSNNNPS 916

  Fly   943 VTSATATPTNNTFGFSTTQKPATPMFGSG---STQQSSTPAVAATKPFTLGGGAPTTPSASPASG 1004
            ..|:||     .|.|.|:.|||. .|||.   :|.:.:.||.:|:.|      ||||       .
pombe   917 TNSSTA-----PFSFGTSNKPAF-SFGSATSKTTSEGTAPAASASAP------APTT-------S 962

  Fly  1005 GFSFSAVATKNTTAPTAGTNLFGSPASASKPSFNFGGNTATQAAAAG--SPAGGFSFATTTKKED 1067
            .|||                      .||..|.|...|| ..|..||  :||.||
pombe   963 AFSF----------------------GASNSSMNKEENT-PMAKDAGDTAPASGF---------- 994

  Fly  1068 SASTNMFGSPNTGVVKPNFSFSSNN-PTPAPTFGGFGAPAAAAPTATST-NQSKPFAFGASTPAA 1130
                           |..|||.:|| |.||..||            ||| ..|..||||
pombe   995 ---------------KSGFSFGANNSPQPASMFG------------TSTPAPSSAFAFG------ 1026

  Fly  1131 APQPPLGGNLFANAVSATQNQTKPSGVFSFGAAKSTAGTTAGNAPFSFGGASAGGIASPPSNQGL 1195
                             .|:.|.|:....||...:||.....:..|:|          .|||.|.
pombe  1027 -----------------NQSGTNPAAPAGFGGITNTATNNPPSTGFTF----------TPSNAGS 1064

  Fly  1196 NTAKPFSFGGAGGTPAPN----------VFGSPAPAPPASN-PTGGFNFGGVSPAQQANAGNMFA 1249
            ..|..|   |||.||.|:          .|||..|:.|||| |:.||:||..:|: ..||....:
pombe  1065 TAAPMF---GAGNTPNPSGSINNASQAFAFGSGEPSNPASNPPSTGFSFGAATPS-AFNASASQS 1125

  Fly  1250 PTP 1252
            |.|
pombe  1126 PAP 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14712	NP_650096.1	Nucleoporin_FG2	954..>1180	CDD:292589	62/232 (27%)
nup124	NP_593213.1	Nup_retrotrp_bd	1072..1158	CDD:287557	23/58 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1436
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23193
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.150