Protein Alignment CG14712 and npp-7

DIOPT Version :9

• Sequence 1: NP_650096.1
• Gene: CG14712 / 41397
• FlyBaseID: FBgn0037924
• Length: 1266
• Species: Drosophila melanogaster
• Sequence 2: NP_001370374.1
• Gene: npp-7 / 172234
• WormBaseID: WBGene00003793
• Length: 1217
• Species: Caenorhabditis elegans
• Alignment Length: 1351
• Identity: 325/1351 - (24%)
• Similarity: 500/1351 - (37%)
• Gaps: 380/1351 - (28%)

  Fly   151 SGNTLSSLLRSNSLVGLVPKTTEQEQLSRENRPILHPPHPQHESEPTRS-VLEELKEISRKRINT 214
            ||...||:.|..|:.....|:.:.::.:.|.     ..:...:|.|:.| .|:.:..:.
 Worm     5 SGGFFSSVGRFFSVGASATKSKDGDKSNDEG-----TSNSSSKSSPSASPALKNILSVD------ 58

  Fly   215 EDTQQAQDYTKRSCQQNVDFVDFVAHHRQQQKLRNLQQ---QQNQSFKRQRELTV-SVPLRHHST 275
            .:.:.|.|.|..:..||         ||...:||.|..   .:..|.....|:.| :||....||
 Worm    59 NEAKIASDETSVNTSQN---------HRIGSRLRYLSPTALDRRTSASNGLEIDVDAVPDIFFST 114

  Fly   276 SLSAASPALQHMNSNGTISPTQSPEQVAKRPNCSYSNDITSSLSSSCRHSNKRKLLDMRERFQHS 340
            ...:.:...|....:..|.|.....:..||......:.:..:|:||.  :|:|| :||....:.:
 Worm   115 PAVSTNRKRQLTELDKQILPQSFRSESVKRSRFLNRSLLEPTLNSSM--NNERK-MDMTWCGELT 176

  Fly   341 KNDTLAS----------------GGSSPENSPENVAKIQ-RKVDAEAVSKAMSMPVVTVA----- 383
            .|.:.||                .||....:.|...|:: ....|:.|.: |||....:|
 Worm   177 ANHSPASSITNFSLLSRRSGATTNGSLSTRTQEIFKKLEGANTPAKEVQR-MSMLRAGIARPEKW 240

  Fly   384 ------AVPASRAISA--PAIQK---AVPQVTEKPKLTL-FNARQSQTIAEQPRPDLSSPEVDAG 436
                  .||...|...  |.::|   |:|...:....|: .:||::....:..|...||...|.|
 Worm   241 GSFSESKVPNGSATGTPPPPLKKAGDAIPSRIQLISKTMGMSARRAPYWTDLTRKRTSSKNGDTG 305

  Fly   437 EYAGIQFVK----PKQQNSMLAAKNPSVERTHKTKLAIMLSG----------LKGELYLGEP--- 484
            ....::.:.    ..:.:|:.:...|:.::|..|.....::.          :||.  .|:|
 Worm   306 SSDSMKSLNGNFATAELSSLFSLDLPAPKKTASTASTTTINSSNSRKQHASIMKGP--DGKPVSR 368

  Fly   485 ---------DELDAPAPKSAPAPVTLPTPVKPIIIAP---------------VTTSTTTVTSTAT 525
                     :|:|..:.|..|.|.|.....:|:.:||               .|.....||:..|
 Worm   369 NTFKLSDDIEEVDEDSQKLPPIPTTTLQNPQPLKLAPEYAPKRGFLDDLAFSFTAPVDLVTAVGT 433

  Fly   526 ISTSAPSKPIILSNQVIKPADVPNTNSTGSVPKLVLGQPAPPAKTEQT----------------P 574
            ..|::.:.    |::..:.:...|..||........|..:...::|.:                |
 Worm   434 AKTASTAS----SHKASESSSESNAESTEKQTSESSGNESDSEESEDSEVDVGEENGSEVKESRP 494

  Fly   575 PKPIDKVPAA------QADIPPKFELSTKPVTPATSSQPLISFGT-------------------- 613
            ....|.:.:|      ..|..||.....:||..|.:  |::..|:
 Worm   495 QTSADTISSAGGSNQSSKDSSPKVAKDAEPVVVAPA--PVVDAGSKKWECQSCFCSWDSTLSECG 557

  Fly   614 -------------PKSTAAPS--------------------FSFGSATNTTSSTIANITNTTTSK 645
                         |||...||                    |.|||..:|| :|||:.|:.|
 Worm   558 ACGEARPGGSGTGPKSQPKPSEKQLVSNLSSFASNTPSTVKFGFGSGASTT-TTIASTTSNT--- 618

  Fly   646 PIFSFGQTPANGPTVGGLSGF-KTEAPATTSVSTTNPGTQVTSTTTFGVTPPKTTTTVAPTTTVS 709
              ..||    :|.:|..|.|. ||.||..|:|..|.|    .:.||....|....|:.:..|.|.
 Worm   619 --IPFG----SGSSVAPLFGAPKTTAPPPTTVPATIP----VAPTTIASAPVAAVTSSSNGTRVD 673

  Fly   710 LNFGQPMPSFGAAD-----------------------TGVKPMFSFGKSNNLSSGTPTTNGSDAA 751
            ......|.|..|:|                       ...||:.|.|  :.:|.|.    |...|
 Worm   674 WECPDCMVSNKASDDKCPCCSHVKYASAEASSNVFGNRAFKPLSSTG--STISFGV----GGSTA 732

  Fly   752 AAKPAVFSFGGSTTQPAAAAPTPVFGSLSKPL--GEGFASPGANKSETTKPSIFGNLDNGLGNAM 814
            ..:|:.|:||.|.|...|...||.||..:||.  ......|.|.:...|..|:|||:
 Worm   733 TTQPSAFAFGLSKTTEVAPTSTPAFGLSAKPAVSSAPVEKPSAPEVPKTAGSLFGNI-------- 789

  Fly   815 KSSTNVAATTAAELPKPFGFAATTTA----AG----GGSTATNLFSFGGTATSKAAEPAPASQKN 871
             :....:|||:...|   |.|::|::    ||    ||||. ::|:...|.|::.|:|      .
 Worm   790 -AKPADSATTSFLAP---GAASSTSSLAPTAGSSLFGGSTG-SIFNLNKTNTTETAKP------G 843

  Fly   872 LFGL-----NATTTTPFAFGGAAAGAADKSENKDNKP-IAFAFGAGNNSAVANPSGVFSFGGTDK 930
            |||.     ...||||.:.  |...:.|.:::|...| ||.......||:..:..|...||.:..
 Worm   844 LFGSILDKETHVTTTPVSV--ALPSSTDSTQSKSAIPTIAPTMSLFGNSSTGSFGGSSMFGNSKT 906

  Fly   931 SAPP-----AFGSGTTS---VTSATATPT-NNTFGFSTTQKPATPMFGSGSTQQSST-----PAV 981
            ..|.     :||:.||:   |::|||... .|.|| |.:...:|.:||:||:..::.     ||.
 Worm   907 ELPKISSTLSFGNPTTAAAPVSTATAEAVKTNVFG-SNSASASTSLFGAGSSSTATNLFTTKPAD 970

  Fly   982 AAT-----KPFTLG-GGAPTTPSASPASGGFSFSAVATKNTTAPTAGTNLFGSPASASKPSF-NF 1039
            :.|     ||.:.| ....||...:||..|. ||:.:.|..         ||.......|.| .|
 Worm   971 STTSSIFGKPISFGDDSGTTTTDGAPAKRGL-FSSDSQKLQ---------FGGQQKVEMPKFTGF 1025

  Fly  1040 GGNTATQAAAAGSPAGGFSFATTTKKEDSASTN--MFGSPNTGVVKPNFSFSSNNPT---PAPTF 1099
            |...:|.:..:||..||            ||||  |||.|::..: |.||.|:::.|   |:.|.
 Worm  1026 GNPASTASTTSGSLFGG------------ASTNPPMFGGPSSSSI-PAFSTSNSSSTSGFPSSTA 1077

  Fly  1100 GGFGAPAAAAPTATSTNQSKPF-AFGASTPAAAPQPPLG-----GNLFANAVSATQNQ---TKPS 1155
            ..||       .|.:|:.|..| ||| :.|:   ||.|.     .:||..|.:.:.|.   |..:
 Worm  1078 TPFG-------NAGTTSTSGVFGAFG-NKPS---QPGLSSSSSTNSLFGQAPADSSNPFGGTSNN 1131

  Fly  1156 GVFSFGAAKSTAGTTAGNAPFSFGGASAGGIASPPSNQGLNTAKPFSFGGAGGTPAPNVFGSPAP 1220
            | |:|||:.||.|.|||          .||:              |.||.|         .:.||
 Worm  1132 G-FNFGASSSTTGATAG----------GGGV--------------FQFGNA---------ATSAP 1162

  Fly  1221 APPASNPTGGFNFGG-------VSPAQQANAGNMFAPT-PESRPIRKATRR 1263
            ||.|:...|.|.|||       .:|....||.:..||: ..:|.:..|.||
 Worm  1163 APTAAPGGGAFQFGGNMSVPQAPAPGGMENAFSYQAPSGVGARKMAMARRR 1213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14712	NP_650096.1	Nucleoporin_FG2	954..>1180	CDD:292589	77/251 (31%)
npp-7	NP_001370374.1	RanBP2-type Zn finger	540..559	CDD:275376	0/18 (0%)
		ZnF_RBZ	673..696	CDD:197784	4/22 (18%)
		RanBP2-type Zn finger	674..693	CDD:275376	4/18 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23193
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100