DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF101

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_149981.2 Gene:ZNF101 / 94039 HGNCID:12881 Length:436 Species:Homo sapiens


Alignment Length:290 Identity:74/290 - (25%)
Similarity:118/290 - (40%) Gaps:41/290 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 RILNCRICSRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQMCTTCLDNLQA---AIKFR 63
            |...|::|.::....:||         |||..|.         :|:....|.:.::|   :..||
Human   167 RPYECKVCGKAFNSPNLF---------QIHQRTH---------TGKRSYKCREIVRAFTVSSFFR 213

  Fly    64 Q--RCIIAEKQNLERIECDSKDCSTDPIIYEDIDDNQIESELDESILCPEVKDLPMPSAEK--VS 124
            :  :....||    |.||  |.|. .||.|..:....:.:...|       |........|  :|
Human   214 KHGKMHTGEK----RYEC--KYCG-KPIDYPSLFQIHVRTHTGE-------KPYKCKQCGKAFIS 264

  Fly   125 APTSLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTS 189
            |.....|:.........:.|.:||:.::..|:...|...|:|.|.:.|  ..|.:.|.....|.:
Human   265 AGYLRTHEIRSHALEKSHQCQECGKKLSCSSSLHRHERTHSGGKLYEC--QKCAKVFRCPTSLQA 327

  Fly   190 HTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDAR 254
            |.|.||||:||.|..|.:.|:.....:.|.:.|..|:.|||..|.|:|.....||:|:|.|...:
Human   328 HERAHTGERPYECNKCGKTFNYPSCFRRHKKTHSGEKPYECTRCGKAFGWCSSLRRHEMTHTGEK 392

  Fly   255 NHYCYVCQKHFKRISHLMTHLSSNIHKRKE 284
            ...|..|.|.|...::|..|..:::..|.:
Human   393 PFDCKQCGKVFTFSNYLRLHERTHLAGRSQ 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 15/74 (20%)
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 6/21 (29%)
zf-H2C2_2 186..211 CDD:290200 12/24 (50%)
UFD2 <256..>294 CDD:227443 7/29 (24%)
C2H2 Zn finger 258..280 CDD:275368 6/21 (29%)
ZNF101NP_149981.2 KRAB 4..>46 CDD:214630
KRAB 4..43 CDD:279668
C2H2 Zn finger 104..124 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 128..164
lambda-1 149..>209 CDD:212564 12/59 (20%)
C2H2 Zn finger 171..191 CDD:275368 7/28 (25%)
COG5048 <176..357 CDD:227381 50/214 (23%)
C2H2 Zn finger 199..219 CDD:275368 4/19 (21%)
C2H2 Zn finger 227..247 CDD:275368 6/22 (27%)
zf-H2C2_2 240..264 CDD:290200 3/30 (10%)
C2H2 Zn finger 255..276 CDD:275368 4/20 (20%)
C2H2 Zn finger 284..304 CDD:275368 5/19 (26%)
C2H2 Zn finger 312..332 CDD:275368 6/21 (29%)
zf-H2C2_2 324..349 CDD:290200 12/24 (50%)
COG5048 336..>407 CDD:227381 23/70 (33%)
C2H2 Zn finger 340..360 CDD:275368 4/19 (21%)
zf-H2C2_2 353..375 CDD:290200 8/21 (38%)
C2H2 Zn finger 368..388 CDD:275368 8/19 (42%)
zf-H2C2_2 380..404 CDD:290200 8/23 (35%)
C2H2 Zn finger 396..416 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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