DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF577

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_001357376.1 Gene:ZNF577 / 84765 HGNCID:28673 Length:485 Species:Homo sapiens


Alignment Length:297 Identity:82/297 - (27%)
Similarity:127/297 - (42%) Gaps:35/297 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 DLFGPGNG----HLVRQIHSITGVEL-SCKKEISGQMCTTCLDNLQAAIK----------FRQRC 66
            |.|| |.|    |:.|. .::|||:. .|.|..|.:.....|..:.|..|          |.::.
Human   109 DAFG-GYGRSCLHIKRD-KTLTGVKYHRCVKPSSPKSQLNDLQKICAGGKPHECSVCGRAFSRKA 171

  Fly    67 IIAEKQNLERIE----CDSKDCSTDPIIYEDIDDNQIESELDESILCPEVKDLPMPSAEKVSAPT 127
            .:.:.|..||.|    |.  :|....:....:.::|.....::...|.|       ..:..|..:
Human   172 QLIQHQRTERGEKPHGCG--ECGKTFMRKIQLTEHQRTHTGEKPHECSE-------CGKAFSRKS 227

  Fly   128 SLNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTR 192
            .|...:....|..||.|..||:..:.|.....|...|||.|.:.|..  |.::|:.:..||:|.|
Human   228 QLMVHQRTHTGEKPYRCSKCGKAFSRKCRLNRHQRSHTGEKLYGCSV--CGKAFSQKAYLTAHQR 290

  Fly   193 IHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHY 257
            :|||::||.|..|.|.|........|.|.|..|:.|||..|:|:|.|...|.:|:..|...|.:.
Human   291 LHTGDKPYKCSDCGRTFYFKSDLTRHQRIHTGEKPYECSECEKAFRSKSKLIQHQRTHTGERPYS 355

  Fly   258 CYVCQKHFKRISHLMTHLSSNIHKRKEEKLTELAIEQ 294
            |..|.|.|..:|.|:.|..::|   :|..:..|.:|:
Human   356 CRECGKAFAHMSVLIKHEKTHI---RETAINSLTVEK 389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 18/73 (25%)
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 7/21 (33%)
zf-H2C2_2 186..211 CDD:290200 13/24 (54%)
UFD2 <256..>294 CDD:227443 10/37 (27%)
C2H2 Zn finger 258..280 CDD:275368 7/21 (33%)
ZNF577NP_001357376.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
KRAB 25..83 CDD:214630
COG5048 136..>217 CDD:227381 13/82 (16%)
C2H2 Zn finger 160..180 CDD:275368 2/19 (11%)
C2H2 Zn finger 188..208 CDD:275368 3/21 (14%)
COG5048 <194..399 CDD:227381 59/208 (28%)
C2H2 Zn finger 216..236 CDD:275368 4/26 (15%)
C2H2 Zn finger 244..264 CDD:275368 5/19 (26%)
C2H2 Zn finger 272..292 CDD:275368 7/21 (33%)
C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
C2H2 Zn finger 328..348 CDD:275368 7/19 (37%)
C2H2 Zn finger 356..376 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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