DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF397

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:XP_006722621.1 Gene:ZNF397 / 84307 HGNCID:18818 Length:553 Species:Homo sapiens


Alignment Length:289 Identity:81/289 - (28%)
Similarity:122/289 - (42%) Gaps:44/289 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 RILNCRICSRSDAPIDLFGPGNGHLVRQIHSITGVELSCKKEISGQ---MCTTC--LDNLQAAIK 61
            |...|.:|              ||..:|..|:|    ..::..:|:   .|..|  ..:|::.:.
Human   302 RPYRCDVC--------------GHSFKQHSSLT----QHQRIHTGEKPYKCNQCGKAFSLRSYLI 348

  Fly    62 FRQRCIIAEKQNLERIECDSKDCSTDPIIYEDIDDNQIESELDESILCPEVKDLPMPSAEKVSAP 126
            ..||....||. .|..||......:..:|..    .:|.:. :::..|.|        ..|..:.
Human   349 IHQRIHSGEKA-YECSECGKAFNQSSALIRH----RKIHTG-EKACKCNE--------CGKAFSQ 399

  Fly   127 TS--LNHQKSIGGGTGPYVCPDCGRIINNKSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTS 189
            :|  :.||: |..|..||.|.:||:..:..|....|...|||.:.:.|  ..|.::|....||.:
Human   400 SSYLIIHQR-IHTGEKPYECNECGKTFSQSSKLIRHQRIHTGERPYEC--NECGKAFRQSSELIT 461

  Fly   190 HTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDAR 254
            |.|||:||:||.|..|.:.||.|.....|.|.|..|..|:|:.|.|:|..|..|.:|:.||....
Human   462 HQRIHSGEKPYECSECGKAFSLSSNLIRHQRIHSGEEPYQCNECGKTFKRSSALVQHQRIHSGDE 526

  Fly   255 NHYCYVCQKHFKRISHLMTHLSSNIHKRK 283
            .:.|..|.|.|:..|.||.|  ..:|..|
Human   527 AYICNECGKAFRHRSVLMRH--QRVHTIK 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 15/74 (20%)
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 7/21 (33%)
zf-H2C2_2 186..211 CDD:290200 13/24 (54%)
UFD2 <256..>294 CDD:227443 10/28 (36%)
C2H2 Zn finger 258..280 CDD:275368 8/21 (38%)
ZNF397XP_006722621.1 SCAN 46..139 CDD:128708
SCAN 46..134 CDD:280241
COG5048 <297..546 CDD:227381 78/278 (28%)
zf-C2H2 304..326 CDD:278523 7/39 (18%)
C2H2 Zn finger 306..326 CDD:275368 7/37 (19%)
zf-H2C2_2 318..342 CDD:290200 5/27 (19%)
C2H2 Zn finger 334..354 CDD:275368 5/19 (26%)
zf-H2C2_2 346..371 CDD:290200 7/25 (28%)
C2H2 Zn finger 362..382 CDD:275368 3/23 (13%)
zf-H2C2_2 374..399 CDD:290200 5/37 (14%)
C2H2 Zn finger 390..410 CDD:275368 6/28 (21%)
zf-H2C2_2 402..427 CDD:290200 9/25 (36%)
C2H2 Zn finger 418..438 CDD:275368 5/19 (26%)
zf-H2C2_2 431..455 CDD:290200 7/25 (28%)
C2H2 Zn finger 446..466 CDD:275368 7/21 (33%)
zf-H2C2_2 458..482 CDD:290200 12/23 (52%)
C2H2 Zn finger 474..494 CDD:275368 7/19 (37%)
zf-H2C2_2 486..511 CDD:290200 9/24 (38%)
C2H2 Zn finger 502..522 CDD:275368 7/19 (37%)
zf-C2H2 528..550 CDD:278523 8/23 (35%)
C2H2 Zn finger 530..550 CDD:275368 8/21 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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