DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF8

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_066575.2 Gene:ZNF8 / 7554 HGNCID:13154 Length:575 Species:Homo sapiens


Alignment Length:271 Identity:77/271 - (28%)
Similarity:110/271 - (40%) Gaps:47/271 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 IKFRQRCIIAEKQNLERIECDSKDCSTDPIIY---EDIDDNQIESEL------------------ 103
            ::.|:.|:::...|      ...:.|....:|   ..|.|::..|.|                  
Human   176 LRLRENCVLSSSPN------PFPEISRGEYLYTYDSQITDSEHNSSLVSQQTGSPGKQPGENSDC 234

  Fly   104 --DESILCP-------EVKDLPMPSAEKVSAPTSLNH------QKSIGGGTGPYVCPDCGRIINN 153
              |.|...|       :|:|.|....:   ...|.||      .|.|..|..||:|.:||:..:.
Human   235 HRDSSQAIPITELTKSQVQDKPYKCTD---CGKSFNHNAHLTVHKRIHTGERPYMCKECGKAFSQ 296

  Fly   154 KSNFQEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEH 218
            .|:..:|...|||.|.:.|.  .|.:||.....||.|.||||||:||.|..|.|.|:.:.:...|
Human   297 NSSLVQHERIHTGDKPYKCA--ECGKSFCHSTHLTVHRRIHTGEKPYECQDCGRAFNQNSSLGRH 359

  Fly   219 HRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIHKRK 283
            .|.|..|:.|.|..|.|||..:.||..|...|.:.|.:.|..|.|.|:..|.|..|...:..::.
Human   360 KRTHTGEKPYTCSVCGKSFSRTTCLFLHLRTHTEERPYECNHCGKGFRHSSSLAQHQRKHAGEKP 424

  Fly   284 EEKLTELAIEQ 294
            .|....|..||
Human   425 FECRQRLIFEQ 435

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 3/15 (20%)
C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
C2H2 Zn finger 172..194 CDD:275368 8/21 (38%)
zf-H2C2_2 186..211 CDD:290200 15/24 (63%)
UFD2 <256..>294 CDD:227443 9/37 (24%)
C2H2 Zn finger 258..280 CDD:275368 7/21 (33%)
ZNF8NP_066575.2 KRAB 25..85 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 92..130
COG5048 <167..404 CDD:227381 68/238 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 210..237 2/26 (8%)
C2H2 Zn finger 259..279 CDD:275368 4/22 (18%)
C2H2 Zn finger 287..307 CDD:275368 5/19 (26%)
C2H2 Zn finger 315..335 CDD:275368 8/21 (38%)
C2H2 Zn finger 343..363 CDD:275368 6/19 (32%)
C2H2 Zn finger 371..391 CDD:275368 8/19 (42%)
zf-C2H2 397..419 CDD:306579 7/21 (33%)
C2H2 Zn finger 399..419 CDD:275368 7/19 (37%)
zf-C2H2 467..489 CDD:306579
C2H2 Zn finger 469..489 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 488..533
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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