DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6813 and ZNF735

DIOPT Version :9

Sequence 1:NP_001163590.1 Gene:CG6813 / 41396 FlyBaseID:FBgn0037923 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_001152996.1 Gene:ZNF735 / 730291 HGNCID:32466 Length:412 Species:Homo sapiens


Alignment Length:247 Identity:75/247 - (30%)
Similarity:105/247 - (42%) Gaps:37/247 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 CLDNLQAAIKFRQRC--IIAEKQNLER----------IECDSKDCSTDPIIYEDIDDNQIESELD 104
            ||.|.|..|....:|  :.::..|..|          ::|  |.......::..::.:||....:
Human   148 CLSNTQNKIFQTHKCVKVFSKFSNSNRHNARYTGKKHLKC--KKYGKSFCMFSHLNQHQIIHTKE 210

  Fly   105 ESILCPEVKDLPMPSAEKVSAPTSLNH------QKSIGGGTGPYVCPDCGRIINNKSNFQEHTLR 163
            :|..|.|             ...|.||      .|.|..|..||.|.:||:.....||...|...
Human   211 KSYKCEE-------------CGKSFNHSSSGTTHKRILTGEKPYRCEECGKAFRWPSNLTRHKRI 262

  Fly   164 HTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRHRNERRY 228
            |||.|.:.|.  .|.::|.....||:|.||||||:||.|..|.:.||.|.|...|.|.|..|:.|
Human   263 HTGEKPYACE--ECGQAFRRSSTLTNHKRIHTGERPYKCEECGKAFSVSSALIYHKRIHTGEKPY 325

  Fly   229 ECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280
            .|:.|.|:|..|..|:.||:||...:.:.|..|.:.|...|.:..|  ..||
Human   326 TCEECGKAFNCSSTLKTHKIIHTGEKPYTCEECGRTFNCSSTVKAH--KRIH 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6813NP_001163590.1 zf-AD 6..76 CDD:285071 7/25 (28%)
C2H2 Zn finger 144..164 CDD:275368 6/19 (32%)
C2H2 Zn finger 172..194 CDD:275368 7/21 (33%)
zf-H2C2_2 186..211 CDD:290200 14/24 (58%)
UFD2 <256..>294 CDD:227443 7/25 (28%)
C2H2 Zn finger 258..280 CDD:275368 5/21 (24%)
ZNF735NP_001152996.1 KRAB 16..76 CDD:214630
KRAB 16..55 CDD:279668
C2H2 Zn finger 160..179 CDD:275368 3/18 (17%)
COG5048 <167..372 CDD:227381 67/223 (30%)
C2H2 Zn finger 187..207 CDD:275368 4/21 (19%)
zf-H2C2_2 199..224 CDD:290200 6/37 (16%)
C2H2 Zn finger 215..235 CDD:275368 6/32 (19%)
C2H2 Zn finger 243..263 CDD:275368 6/19 (32%)
zf-H2C2_2 255..280 CDD:290200 9/26 (35%)
C2H2 Zn finger 271..291 CDD:275368 7/21 (33%)
zf-H2C2_2 284..307 CDD:290200 13/22 (59%)
C2H2 Zn finger 299..319 CDD:275368 8/19 (42%)
zf-H2C2_2 311..336 CDD:290200 10/24 (42%)
C2H2 Zn finger 327..347 CDD:275368 8/19 (42%)
zf-H2C2_2 340..364 CDD:290200 8/23 (35%)
COG5048 <351..>412 CDD:227381 7/27 (26%)
C2H2 Zn finger 355..375 CDD:275368 5/21 (24%)
zf-H2C2_2 368..391 CDD:290200 3/10 (30%)
C2H2 Zn finger 383..403 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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